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Chemical Structure| 56671-66-0 Chemical Structure| 56671-66-0

Structure of 56671-66-0

Chemical Structure| 56671-66-0

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Product Details of [ 56671-66-0 ]

CAS No. :56671-66-0
Formula : C8H6N2O
M.W : 146.15
SMILES Code : O=CC1=NC=C2C=CC=CN21
MDL No. :MFCD08752619
InChI Key :UFDFAMUXKRGTJE-UHFFFAOYSA-N
Pubchem ID :12222777

Safety of [ 56671-66-0 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of [ 56671-66-0 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 56671-66-0 ]

[ 56671-66-0 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 384-16-7 ]
  • [ 56671-66-0 ]
  • [2-chloro-6-(trifluoromethyl)phenyl](imidazo[1,5-a]pyridin-3-yl)methanol [ No CAS ]
YieldReaction ConditionsOperation in experiment
1.22 g 2-Bromo-1-chloro-3-trifluoromethylbenzene (2.49 g)In tetrahydrofuran (25 mL) at -78 C.,n-Butyllithium (1.58 N hexane solution, 6.10 mL) was added,And the mixture was stirred at the same temperature for 30 minutes.Then, the obtained lithio compoundAt -78 C.,Imidazo [1,5-a] pyridine-3-carboxaldehyde (700 mg) in tetrahydrofuran (25 mL), and the mixture was stirred at -78 C. for 1 hour. Water was added to the reaction solution, and the mixture was extracted three times with ethyl acetate. The organic layer was dried over magnesium sulfate, concentrated under reduced pressure, and then purified by silica gel column chromatography (ethyl acetate / hexane) to obtain the title compound (1.22 g) as a pale yellow solid.
 

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