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Chemical Structure| 56461-20-2 Chemical Structure| 56461-20-2

Structure of 56461-20-2

Chemical Structure| 56461-20-2

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Product Details of [ 56461-20-2 ]

CAS No. :56461-20-2
Formula : C10H8O3
M.W : 176.17
SMILES Code : O=C(C1=CC=CC2=C1CCC2=O)O
MDL No. :MFCD03411485
InChI Key :UEZFIXMZVFIHGO-UHFFFAOYSA-N
Pubchem ID :12542206

Safety of [ 56461-20-2 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of [ 56461-20-2 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 56461-20-2 ]

[ 56461-20-2 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 56461-20-2 ]
  • [ 62830-55-1 ]
  • 8-Iodo-5,10-dihydro-indeno[1,2-b]indole-1-carboxylic acid [ No CAS ]
YieldReaction ConditionsOperation in experiment
5% With hydrogenchloride; In formic acid; EXAMPLE 17 8-Iodo-5,10-dihydro-indeno[1,2-b]indole-1-carboxylic acid 0.6 hydrate 1-Oxo-indan4-carboxylic acid (0.528 g, 2.99 mmol) and <strong>[62830-55-1]4-iodophenylhydrazine hydrochloride</strong> (0.698 g, 2.58 mmol) were mixed together in a Teflon PFA vessel to form a paste in formic acid (2 mL, 96percent) containing 3 drops of concentrated HCl. The vessel was irradiated at full power (760 W) in a CEM Microwave (MDS2000) for one minute (T=140 C, P<50 PSI), allowed to cool for 2 min, then irradiated again for one min (T=140 C, P<50 PSI). The mixture was vacuum filtered hot. The solid was washed with formic acid, and dried on the frit. Chromatography (acetone/hexane) and trituration with diethyl ether gave the title compound (0.059 g, 5percent) as an tan solid: mp 251° C.; 1H NMR (DMSO-d6): delta 3.98 (s, 2H), 7.30-7.37 (m, 2H), 7.49 (t, 1H), 7.77-7.80 (m, 2H), 7.98 (d, 1H), 11.82 (s, 1H), 13.53 (s, 1H); MS [EI, m/z]: 375 [M]+. Elemental analysis for C16H10INO2.0.6(H2O)Calc'd: C, 49.87; H, 2.72; N, 3.63Found: C, 49.59; H, 2.81; N, 3.66
 

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