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Chemical Structure| 5601-58-1 Chemical Structure| 5601-58-1

Structure of 5601-58-1

Chemical Structure| 5601-58-1

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Product Details of [ 5601-58-1 ]

CAS No. :5601-58-1
Formula : C10H18O3
M.W : 186.25
SMILES Code : CC(C(C)CCCCC(OC)=O)=O
MDL No. :MFCD22392011

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Application In Synthesis of [ 5601-58-1 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 5601-58-1 ]

[ 5601-58-1 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 5601-58-1 ]
  • [ 99183-34-3 ]
YieldReaction ConditionsOperation in experiment
75% With hydrogenchloride; water; for 6.0h;Reflux; Example 5. Preparation of 6-methyl-7-oxooctane acid (compound 5) A mixture of diluted (2:1) hydrochloric acid (37 mL) and 6-methyl-7-oxooctane acid, methyl ester (compound 4) (9.11 g; 0.049 mole) was refluxed under stirring for 6 h. The reaction produced two immiscible layers. The reaction mixture was extracted with ether. Ethereal extracts were combined. The solvent was removed and the residue was fractionated under vacuum. Fraction having Bp= 100-143C/0.1-0.01 mm Hg was drawn to obtain 6-methyl-7-oxooctane acid (compound 5) yield of 5.9 g (75%). 1H-NMR (CDCl3), δ (ppm): 1.06 (3H, d, 6-CH3); 1.25-1.39 (3H, m, 5-CH2, 4-CH2); 1.58-1.69 (3H, m, 3-CH2, 4-CH2); 2.12 (3H, s, 8-CH3); 2.33 (2H, t, J=7.5, 2-CH2); 2.5 (1H, m, 6-CH).
 

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