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Chemical Structure| 558442-97-0 Chemical Structure| 558442-97-0

Structure of 558442-97-0

Chemical Structure| 558442-97-0

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Product Details of [ 558442-97-0 ]

CAS No. :558442-97-0
Formula : C10H20N2O
M.W : 184.28
SMILES Code : N[C@H]1CC[C@H](N2CCOCC2)CC1
MDL No. :MFCD09759035

Safety of [ 558442-97-0 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302
Precautionary Statements:P280-P305+P351+P338

Application In Synthesis of [ 558442-97-0 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 558442-97-0 ]

[ 558442-97-0 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 558442-97-0 ]
  • [ 7464-11-1 ]
  • C16H22ClN5OS [ No CAS ]
YieldReaction ConditionsOperation in experiment
67% With potassium phosphate; In acetonitrile; at 85℃; Into a 2000-mL 3-necked round-bottom flask, was placed a solution of compound 23.1 (50 g, 227.19 mmol, 1.00 equiv) in MeCN (1500 mL), K3P04 (145.2 g, 684.03 mmol, 3.01 equiv), and (lr,4r)-4-(morpholin-4-yl)cyclohexan-1-amine (50.4 g, 273.50 mmol, 1.20 equiv). The resulting solution was stirred overnight at 85 C in an oil bath. The reaction mixture was cooled to room remperature, solids were filtered out and the resulting mixture was concentrated under vacuum. The crude product was re-crystallized to furnish 56 g (67%) of intermediate 23.2 as a yellow solid.
 

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