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Chemical Structure| 55364-85-7 Chemical Structure| 55364-85-7

Structure of 55364-85-7

Chemical Structure| 55364-85-7

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Product Details of [ 55364-85-7 ]

CAS No. :55364-85-7
Formula : C9H12N2O2
M.W : 180.20
SMILES Code : COC(=O)CCNC1=NC=CC=C1
MDL No. :MFCD02708568
InChI Key :CKZDJCJSSSCYFN-UHFFFAOYSA-N
Pubchem ID :818199

Safety of [ 55364-85-7 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319-H335
Precautionary Statements:P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P313-P337+P313-P362-P403+P233-P405-P501

Application In Synthesis of [ 55364-85-7 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 55364-85-7 ]

[ 55364-85-7 ] Synthesis Path-Downstream   1~9

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  • [ 109-02-4 ]
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  • [ 211915-62-7 ]
  • [ 125700-67-6 ]
  • [ 211915-63-8 ]
YieldReaction ConditionsOperation in experiment
In N-methyl-acetamide; g 1-Methyl-2-[(4-cyanophenyl)oxymethyl]-imidazo[4,5-b]pyridin-5-yl-carboxylic acid-N-(2-pyridyl)-N-(2-methoxycarbonylethyl)-amide 308 mg (1.0 mMol) of 1-methyl-2-[(4-cyanophenyl)oxymethyl]-5-carboxy-imidazo[4.5-b]pyridine were suspended in 5 ml of dimethylformamide and mixed with 303 mg (3.0 mMol) of N-methyl-morpholine and 321 mg (1.0 mMol) of O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyl-uronium tetrafluoroborate. After 10 minutes at room temperature a solution of 215 mg (1.2 mMol) of <strong>[55364-85-7]methyl N-(2-pyridyl)-3-amino-propionate</strong> in 2 ml of dimethylformamide was added, whereupon a clear solution was obtained. After 12 hours at room temperature the reaction solution was stirred into ice-water. After extracting 3 times with ethyl acetate the combined organic extracts were washed with a saline solution, dried over sodium sulphate and evaporated down. The residue obtained was chromatographed on silica gel with dichloromethane/ethanol (90:1 to 25:1). Yield: 165 mg of white powder (35% of theory), C25 H12 N6 O4 (407.50) Melting point: 139-140 C.
  • 9
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  • [ 83-13-6 ]
  • [ 1263050-05-0 ]
 

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