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Chemical Structure| 53698-45-6 Chemical Structure| 53698-45-6

Structure of 53698-45-6

Chemical Structure| 53698-45-6

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Product Details of [ 53698-45-6 ]

CAS No. :53698-45-6
Formula : C12H11NO
M.W : 185.22
SMILES Code : COC1=NC=CC=C1C2=CC=CC=C2
MDL No. :MFCD14702086

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Application In Synthesis of [ 53698-45-6 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 53698-45-6 ]

[ 53698-45-6 ] Synthesis Path-Downstream   1~2

  • 2
  • [ 53698-45-6 ]
  • [ 24228-13-5 ]
YieldReaction ConditionsOperation in experiment
350 mg With acetic acid; potassium iodide; for 6.0h;Reflux; To a solution of 2-6 (800 mg, 4.32 mmol) in glacial acetic acid (20 mL), potassium iodide (2.15 g, 13.0 mmol) was added. The mixture was heated to reflux for 6 hours then was cooled to room temperature and concentrated. The residue was taken up in chloroform and washed with saturated aqueous sodium bicarbonate and brine. The organic layer was dried over magnesium sulfate, filtered, and concentrated under reduced pressure to give 3-phenylpyridin-2(1H)-one (2-7, 350 mg) as a yellow powder.
 

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