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Chemical Structure| 53220-41-0 Chemical Structure| 53220-41-0

Structure of 53220-41-0

Chemical Structure| 53220-41-0

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Product Details of [ 53220-41-0 ]

CAS No. :53220-41-0
Formula : C12H14ClNO
M.W : 223.70
SMILES Code : O=C(C1=CC=C(Cl)C=C1)C2CCNCC2
MDL No. :MFCD04113538

Safety of [ 53220-41-0 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P233-P260-P261-P264-P270-P271-P280-P301+P312-P302+P352-P304-P304+P340-P305+P351+P338-P312-P321-P330-P332+P313-P337+P313-P340-P362-P403-P403+P233-P405-P501

Application In Synthesis of [ 53220-41-0 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 53220-41-0 ]

[ 53220-41-0 ] Synthesis Path-Downstream   1~6

  • 1
  • [ 53220-41-0 ]
  • [ 663193-80-4 ]
  • [ 1427595-75-2 ]
YieldReaction ConditionsOperation in experiment
With potassium carbonate; In N,N-dimethyl-formamide; at 50.0℃; Intermediate (138.1 ): [1-(6-Amino-5-bromo^yrimidin-4-yl)-piperidin-4-yl]-(4-chloro- phenyl)-methanoneThe mixture of 5-bromo-6-chloro-pyrimidine-4-ylamine (2.0 g, 9.59 mmol, 1 .0 eq), 4- chlorophenyl-piperidin-4-yl-methanone (2.36 g, 10.55 mmol, 1 .10 eq) and potassium carbonate (6.63 g, 47.97 mmol, 5.0 eq) in DMF (5 ml_) was stirred at 50 C overnight. After pouring the reaction mixture to water, the precipitate was collected to give Intermediate (138.1 ). LC-MS (M+1 : 396, obsd: 396).
  • 2
  • [ 53220-41-0 ]
  • [ 88377-29-1 ]
  • (1-(2-bromo-3-hydroxybenzoyl)piperidin-4-yl)(4-chlorophenyl)methanone [ No CAS ]
  • 3
  • [ 53220-41-0 ]
  • [ 88377-29-1 ]
  • (1-(2-bromo-3-methoxybenzoyl)piperidin-4-yl)(4-chlorophenyl)methanone [ No CAS ]
  • 4
  • [ 53220-41-0 ]
  • [ 54413-93-3 ]
  • (4-(4-chlorobenzoyl)piperidin-1-yl)(2-iodo-5-methoxyphenyl)methanone [ No CAS ]
  • 5
  • [ 53220-41-0 ]
  • [ 74440-82-7 ]
  • (4-(4-chlorobenzoyl)piperidin-1-yl)(3-hydroxy-5-iodophenyl)methanone [ No CAS ]
  • 6
  • [ 53220-41-0 ]
  • [ 74440-82-7 ]
  • (4-(4-chlorobenzoyl)piperidin-1-yl)(3-iodo-5-methoxyphenyl)methanone [ No CAS ]
 

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