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Chemical Structure| 52574-08-0 Chemical Structure| 52574-08-0

Structure of S-Acm-β-Mercaptopropionic Acid
CAS No.: 52574-08-0

Chemical Structure| 52574-08-0

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Product Details of [ 52574-08-0 ]

CAS No. :52574-08-0
Formula : C6H11NO3S
M.W : 177.22
SMILES Code : O=C(O)CCSCNC(C)=O
MDL No. :MFCD00236748

Safety of [ 52574-08-0 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of [ 52574-08-0 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 52574-08-0 ]

[ 52574-08-0 ] Synthesis Path-Downstream   1~4

  • 1
  • [ 625-51-4 ]
  • [ 107-96-0 ]
  • [ 52574-08-0 ]
YieldReaction ConditionsOperation in experiment
With trifluoroacetic acid; 3-((acetamidomethyl)sulphanyl)propanoic acid (Acm) (IV.2) 3-mercaptopropanoic acid (1.64 ml; 19 mmol) is dissolved into trifluoroacetic acid (30 ml). <strong>[625-51-4]N-(hydroxymethyl)acetamide</strong> (1.6 g; 19 mmol) is next added. After stirring for 30 minutes at room temperature, TFA is evaporated off to obtain IV.2: HPLC tR 7.1 min. (linear gradient, 5-65% B, 20 min); 1H NMR (300 MHz, CDCl3, 298 K) delta 12.4 (s, COOH, 1H); 7.74 (d, NH, J=5.8 Hz, 1H); 4.34 (d, SCH2NH, J=6 Hz, 2H); 2.81 (t, CH2SCH2NH, J=6.4 Hz, 2H); 2.67 (t, CH2COOH, J=6.4 Hz, 2H); 2.1 (s, NHCOCH3, 3H); 13C NMR (300 MHz, CDCl3, 298 K) 177.45 (CO); 174.63 (CO); 41.60 (CH2); 34.37 (CH2); 25.67 (CH2); 21.46 (CH3).
  • 2
  • [ 13734-34-4 ]
  • [ 52574-08-0 ]
  • [ 13850-91-4 ]
  • (S)-2-((R)-2-[3-(Acetylamino-methylsulfanyl)-propionyl]-methyl-amino}-3-methyl-butyrylamino)-3-phenyl-propionic acid [ No CAS ]
  • 3
  • [ 115962-35-1 ]
  • [ 52574-08-0 ]
  • [ 13850-91-4 ]
  • (S)-2-((R)-2-[3-(Acetylamino-methylsulfanyl)-propionyl]-methyl-amino}-3-methyl-butyryl)-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid [ No CAS ]
  • 4
  • [ 27144-18-9 ]
  • [ 625-51-4 ]
  • [ 52574-08-0 ]
 

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