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Chemical Structure| 52153-09-0 Chemical Structure| 52153-09-0
Chemical Structure| 52153-09-0
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Product Details of [ 52153-09-0 ]

CAS No. :52153-09-0
Formula : C6H10O6
M.W : 178.14
SMILES Code : O=C1[C@@H](O)[C@H](O)[C@@H](O)[C@H](CO)O1
MDL No. :MFCD00067388
InChI Key :PHOQVHQSTUBQQK-KLVWXMOXSA-N
Pubchem ID :1549082

Safety of [ 52153-09-0 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319
Precautionary Statements:P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

Application In Synthesis of [ 52153-09-0 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 52153-09-0 ]

[ 52153-09-0 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 299-27-4 ]
  • [ 52153-09-0 ]
  • [ 74464-44-1 ]
YieldReaction ConditionsOperation in experiment
Example 4 Synthesis of L-Glucononlactone Procedure A stirred solution of crude <strong>[299-27-4]potassium gluconate</strong> (0.24 moles) in water was acidified to pH 2.5 with concentrated HCl and then warmed to around 50 C. about 80% of the water was removed under vacuum distillation. To the warm solution isopropanol (800 mL) was added and the solution was heated to reflux azeotroping drying of the solution final volume about 200 mL. This lead to the formation of 1,4-lactone (major) and 1,5-lactone (minor). The solution was cooled to room temperature and neutralised by the addition of triethylamine to give pH 7. Inorganic salts were removed by filtration and the filtrate was collected and was used for the next step without further purification.
 

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