Home Cart Sign in  
Chemical Structure| 51762-69-7 Chemical Structure| 51762-69-7

Structure of 51762-69-7

Chemical Structure| 51762-69-7

*Storage: {[sel_prStorage]}

*Shipping: {[sel_prShipping]}

,{[proInfo.pro_purity]}

4.5 *For Research Use Only !

{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

Change View

Size Price VIP Price

US Stock

Global Stock

In Stock
{[ item.pr_size ]} Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

  • {[ item.pr_size ]}

In Stock

- +

Please Login or Create an Account to: See VIP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

  • 1-2 Day Shipping
  • High Quality
  • Technical Support
Product Citations

Alternative Products

Product Details of [ 51762-69-7 ]

CAS No. :51762-69-7
Formula : C14H8O3S
M.W : 256.28
SMILES Code : O=C(C1=CC=CC(SC2=C3C=CC=C2)=C1C3=O)O

Safety of [ 51762-69-7 ]

Application In Synthesis of [ 51762-69-7 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 51762-69-7 ]

[ 51762-69-7 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 51762-69-7 ]
  • [ 119692-59-0 ]
  • [ 1214748-78-3 ]
YieldReaction ConditionsOperation in experiment
With 2,6-di-tert-butyl-4-methyl-phenol; tetrabutylammomium bromide; In dimethyl sulfoxide; acetonitrile; for 24.0h;Reflux; Synthesis of TX-1; [0141] Synthesis of θ-oxo-ΘH-thioxanthene-i-carboxylic acid-3-(4-acryloyloxy- butoxy)2-hydroxy-propyl ester:A reaction mixture containing θ-oxo-ΘH-thioxanthene-i -carboxylic acid (3.8 g, 15 mmol), acetonitrile (40 tnL), dimethylsulfoxide (23 mL), tetrabutylammonium bromide (0.5 g, 1.5 mmo[)and 2,6-d i-tert-butyl-4- methylphenol (0.03 g, 0.122 mmol) was heated to reflux. At this temperature 4-hydroxybutylacryfate giycidylether (2.4 g, 12.2 mmol) was added and the mixture was allowed to stir at reflux temperature for 24 hours.The mixture was cooled to room temperature and filtered to remove the residual, undissolved θ-oxo-ΘH-thioxanthene-i-carboxylic acid. The filtrate was evaporated under reduced pressure. The residual oil, which contains dimethylsulfoxide, was brought in distilled water. After stirring for 1 hour the aqueous layer was decanted off. The residue was dissolved in dichloromethane (100 mL) and extracted with a mixture of an aqueous solution of sodium hydroxide (1 N) and distilled water (1/2).The organic layer was separated, dried on MgSO4, filtered and evaporated to provide 4.9 g of a yellow oil.The product was purified on a SVP D40 Merck Np Column using dichloromethane / ethyl acetate (80/20) as eluent, to afford 2.6 g of a yellow oil.
With 2,6-di-tert-butyl-4-methyl-phenol;tetrabutylammomium bromide; In dimethyl sulfoxide; acetonitrile; for 24.0h;Reflux; A reaction mixture containing 9-oxo-9H-thioxanthene-1-carboxylic acid (3.8 g, 15 mmol), acetonitrile (40 mL), dimethylsulfoxide (23 mL), tetrabutylammonium bromide (0.5 g, 1.5 mmol)and 2,6-di-tert-butyl-4-methylphenol (0.03 g, 0.122 mmol) was heated to reflux. At this temperature 4-hydroxybutylacrylate glycidylether (2.4 g, 12.2 mmol) was added and the mixture was allowed to stir at reflux temperature for 24 hours. The mixture was cooled to room temperature and filtered to remove the residual, undissolved 9-oxo-9H-thioxanthene-1-carboxylic acid. The filtrate was evaporated under reduced pressure. The residual oil, which contains dimethylsulfoxide, was brought in distilled water. After stirring for 1 hour the aqueous layer was decanted off. The residue was dissolved in dichloromethane (100 mL) and extracted with a mixture of an aqueous solution of sodium hydroxide (1 N) and distilled water (1/2). The organic layer was separated, dried on MgSO4, filtered and evaporated to provide 4.9 g of a yellow oil. The product was purified on a SVP D40 Merck Np Column using dichloromethane / ethyl acetate (80/20) as eluent, to afford 2.6 g of a yellow oil.
2.6 g With 2,6-di-tert-butyl-4-methyl-phenol; tetrabutylammomium bromide; In dimethyl sulfoxide; acetonitrile; for 24.0h;Reflux; Synthesis of 9-oxo-9H-thioxanthene-1-carboxylic acid-3-(4-acryloyloxy-butoxy)-2-hydroxy-propyl ester A reaction mixture containing 9-oxo-9H-thioxanthene-1-carboxylic acid (3.8 g, 15 mmol), acetonitrile (40 mL), dimethylsulfoxide (23 mL), tetrabutylammonium bromide (0.5 g, 1.5 mmol) and 2,6-di-tert-butyl-4-methylphenol (0.03 g, 0.122 mmol) was heated to reflux. At this temperature 4-hydroxybutylacrylate glycidylether (2.4 g, 12.2 mmol) was added and the mixture was allowed to stir at reflux temperature for 24 hours. The mixture was cooled to room temperature and filtered to remove the residual, undissolved 9-oxo-9H-thioxanthene-1-carboxylic acid. The filtrate was evaporated under reduced pressure. The residual oil, which contains dimethylsulfoxide, was brought in distilled water. After stirring for 1 hour the aqueous layer was decanted off. The residue was dissolved in dichloromethane (100 mL) and extracted with a mixture of an aqueous solution of sodium hydroxide (1N) and distilled water (1/2). The organic layer was separated, dried on MgSO4, filtered and evaporated to provide 4.9 g of a yellow oil. The product was purified on a SVP D40 Merck Np Column using dichloromethane/ethyl acetate (80/20) as eluent, to afford 2.6 g of a yellow oil.
  • 2
  • [ 51762-69-7 ]
  • [ 128-37-0 ]
  • [ 119692-59-0 ]
  • [ 1214748-78-3 ]
YieldReaction ConditionsOperation in experiment
With sodium hydroxide; tetrabutylammomium bromide; In dichloromethane; water; dimethyl sulfoxide; ethyl acetate; acetonitrile; Synthesis of comparative initiator CTX-1 Synthesis of 9-oxo-9H-thioxanthene-1-carboxylic acid-3-(4-acryloyloxy-butoxy)-2-hydroxy-propyl ester: A reaction mixture containing 9-oxo-9H-thioxanthene-1-carboxylic acid (3.8 g, 15 mmol), acetonitrile (40 mL), dimethylsulfoxide (23 mL), tetrabutylammonium bromide (0.5 g, 1.5 mmol) and 2,6-di-tert-butyl-4-methylphenol (0.03 g, 0.122 mmol) was heated to reflux. At this temperature 4-hydroxybutylacrylate glycidylether (2.4 g, 12.2 mmol) was added and the mixture was allowed to stir at reflux temperature for 24 hours. The mixture was cooled to room temperature and filtered to remove the residual, undissolved 9-oxo-9H-thioxanthene-1-carboxylic acid. The filtrate was evaporated under reduced pressure. The residual oil, which contains dimethylsulfoxide, was brought in distilled water. After stirring for 1 hour the aqueous layer was decanted off. The residue was dissolved in dichloromethane (100 mL) and extracted with a mixture of an aqueous solution of sodium hydroxide (1N) and distilled water (1/2). The organic layer was separated, dried on MgSO4, filtered and evaporated to provide 4.9 g of a yellow oil. The product was purified on a SVP D40 Merck Np Column using dichloromethane/ethyl acetate (80/20) as eluent, to afford 2.6 g of a yellow oil.
 

Historical Records

Technical Information

Categories