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Chemical Structure| 5078-07-9 Chemical Structure| 5078-07-9

Structure of 5078-07-9

Chemical Structure| 5078-07-9

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Product Details of [ 5078-07-9 ]

CAS No. :5078-07-9
Formula : C8H7NO2
M.W : 149.15
SMILES Code : OC1=CC=C2N=C(C)OC2=C1
MDL No. :MFCD00464862
InChI Key :RZKJWYDRDBVDJJ-UHFFFAOYSA-N
Pubchem ID :676504

Safety of [ 5078-07-9 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of [ 5078-07-9 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 5078-07-9 ]

[ 5078-07-9 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 5078-07-9 ]
  • [ 4728-12-5 ]
  • [ 1036393-28-8 ]
YieldReaction ConditionsOperation in experiment
87% With triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; toluene; at 20℃;Cooling with ice; To tetrahydrofuran solution (40 ml) of 4 (1.74 g, 11.67 mmol), 14 (2.05 g, 14.00 mmol) and triphenylphosphine (3.68 g, 14.00 mmol) were added, and 40percent diethyl azodicarboxylate/toluene solution (6.11 g, 14.00 mmol) was dropped while ice-cooling with shaking, and the mixture was stirred at room temperature for 3 days. The reaction mixture was evaporated to dryness under reduced pressure, and the residue was purified by silica gel column chromatography (solvent: ethyl acetate/n-hexane = 4/1), to obtain 30 (2.80 g, 87percent) of colorless solid substance. APCI-MS m/z 278[M+H]+
 

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