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Chemical Structure| 507-25-5 Chemical Structure| 507-25-5

Structure of 507-25-5

Chemical Structure| 507-25-5

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Product Details of [ 507-25-5 ]

CAS No. :507-25-5
Formula : CI4
M.W : 519.63
SMILES Code : IC(I)(I)I
MDL No. :MFCD00001067
InChI Key :JOHCVVJGGSABQY-UHFFFAOYSA-N
Pubchem ID :10487

Safety of [ 507-25-5 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319
Precautionary Statements:P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313

Application In Synthesis of [ 507-25-5 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 507-25-5 ]

[ 507-25-5 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 507-25-5 ]
  • C10H15I2NO2 [ No CAS ]
  • [ 107259-06-3 ]
  • [ 1268810-09-8 ]
YieldReaction ConditionsOperation in experiment
250mL three neck flask was added triphenylphosphine (11. 3g, 0 · 044mol, 4eq) and DCM (255g), the reactionWas cooled to 0~5 C, was added CI4 (11. 4g, 0. 022mol, 2eq), stirred for 30min. Four batches Compound 2Α (2g, 0. 01 lmo 1,1 eq), heat obvious, 0 C reaction 0. 5h. Filtered to remove solids, and concentrated, brush silica gel, eluent concentrationReduced to give a yellow solid 4. 3g. ESI / MS: m / z = 436 (M + H) +.[0073] (50mL) of the pale yellow solid was added THF, cooled to -78 C, was added dropwise 2. 5Μ n-BuLi / hexane solution(13mL, 0 · 033mol, 3eq), - 78. . The reaction 30min, slowly warmed to -40. . The reaction 30min. -40. . Slowly droppedWater (50 mL), was slowly warmed to room temperature and extracted with ethyl acetate (50mL * 2), dried and concentrated to give a solid. N-Heptane (10g)Was added to the solid, stirred for 30min, filtered and dried to afford Compound 3A as a white solid (1. 55g, yield: 79%, pureDegree: 94 · 6%)
  • 2
  • [ 507-25-5 ]
  • [ 107259-06-3 ]
  • C10H15I2NO2 [ No CAS ]
YieldReaction ConditionsOperation in experiment
4.3 g 250mL three neck flask was added triphenylphosphine (11. 3g, 0 · 044mol, 4eq) and DCM (255g), the reactionWas cooled to 0~5 C, was added CI4 (11. 4g, 0. 022mol, 2eq), stirred for 30min. Four batches Compound 2Α (2g, 0. 01 lmo 1,1 eq), heat obvious, 0 C reaction 0. 5h. Filtered to remove solids, and concentrated, brush silica gel, eluent concentrationReduced to give a yellow solid 4. 3g.
 

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