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Chemical Structure| 5021-52-3 Chemical Structure| 5021-52-3

Structure of 5021-52-3

Chemical Structure| 5021-52-3

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Product Details of [ 5021-52-3 ]

CAS No. :5021-52-3
Formula : C6H5N3O2S
M.W : 183.19
SMILES Code : O=C1NC(SC(C)=N2)=C2C(N1)=O
MDL No. :MFCD18642541

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Application In Synthesis of [ 5021-52-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 5021-52-3 ]

[ 5021-52-3 ] Synthesis Path-Downstream   1~3

  • 1
  • [ 5021-52-3 ]
  • [ 7464-11-1 ]
YieldReaction ConditionsOperation in experiment
54% With N,N-dimethyl-aniline; trichlorophosphate; at 130℃; for 4.0h; To a mixture of 2-methyl-4H-thiazolo[5,4-rf]pyrimidine-5,7-dione (7.5 g, 0.041 mol) in N^V-dimethylaniline (3.7 mL, 0.029 mol) was added phosphorous oxychloride (38.0 mL, 0.410 mol) and the mixture heated at 130 C for 4 h. The resulting black solution was cooled to RT, then carefully quenched with crushed ice and H2O, before being extracted with EtOAc. The organic layer was isolated, dried (MgSO4) and concentrated in vacuo to give a yellow solid. The solid was dissolved in DCM, then washed with an aqueous solution OfNaHCO3 <n="47"/>followed by brine, dried (Na2SO4) and concentrated in vacuo to give the title compound as a pale yellow solid (4.90 g, 54 %).1H NMR (300 MHz, CDCl3): delta 2.95 (s, 3 H).
  • 2
  • [ 5021-52-3 ]
  • [ 7464-11-1 ]
  • 3
  • [ 31785-05-4 ]
  • [ 5021-52-3 ]
 

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