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Chemical Structure| 479079-15-7 Chemical Structure| 479079-15-7

Structure of 479079-15-7

Chemical Structure| 479079-15-7

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Product Details of [ 479079-15-7 ]

CAS No. :479079-15-7
Formula : C7H15N3O3
M.W : 189.21
SMILES Code : O=C(OC(C)(C)C)NCC(NO)=N
MDL No. :MFCD11052410

Safety of [ 479079-15-7 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P280-P301+P312-P302+P352-P305+P351+P338

Application In Synthesis of [ 479079-15-7 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 479079-15-7 ]

[ 479079-15-7 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 479079-15-7 ]
  • [ 1077-96-9 ]
  • [ 1309446-90-9 ]
YieldReaction ConditionsOperation in experiment
75% To a round bottomed flask was added 5-Fluoro-lH-indazole-3-carboxylic acid from Production Example 4 (2.73 g, 0.015 mol, 1 equiv.) in DMF (40 mL) under nitrogen. Carbodiimidazole (CDI) (2.98 g, 0.018 mol, 1.1 equiv.) was added to the resulting yellow solution and this was stirred at room temperature for 30 minutes. N-(tert- butoxycarbonyl)-2-aminoacetarnidoxime (3.46 g, 0.018 mol, 1.1 equiv.) in DMF (20 mL) was then added and the solution was stirred overnight at room temperature. The solvent was removed in vacuo on a high vacuum pump, and the crude solid was dissolved in dichloromethane. The resulting precipitate was filtered off and dried in in vacuo to give a light brown powder (4.04 g, 75%); LC-MS-EI 352.4(MH+, 100).
 

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