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Chemical Structure| 4747-72-2 Chemical Structure| 4747-72-2

Structure of 4747-72-2

Chemical Structure| 4747-72-2

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Product Details of [ 4747-72-2 ]

CAS No. :4747-72-2
Formula : C4H5NO
M.W : 83.09
SMILES Code : O=C=NC1CC1
MDL No. :MFCD02093694
InChI Key :DBBRJAWSDTYYBM-UHFFFAOYSA-N
Pubchem ID :637659

Safety of [ 4747-72-2 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H225-H301-H311-H315-H319-H331-H335
Precautionary Statements:P210-P233-P235-P240-P241-P242-P243-P260-P261-P264-P270-P271-P280-P301+P310-P302+P352-P303+P361+P353-P304-P304+P340-P305+P351+P338-P311-P312-P321-P322-P330-P332+P313-P337+P313-P340-P361-P362-P363-P370+P378-P403-P403+P233-P403+P235-P405-P501
Class:6.1(3)
UN#:3080
Packing Group:

Application In Synthesis of [ 4747-72-2 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 4747-72-2 ]

[ 4747-72-2 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 593-71-5 ]
  • [ 4747-72-2 ]
  • [ 19047-31-5 ]
YieldReaction ConditionsOperation in experiment
95% With methyllithium; lithium bromide; In diethyl ether; at -78℃; for 1h; General procedure: To a cooled (-78C) solution of isocyanate (1.0 equiv) in dry Et2O (1 M concentration) was added the dihalomethane derivative (1.5 equiv). After 2 min, an ethereal solution of 1.5 M MeLi-LiBr (1.25equiv) was added dropwise over 5 min. The resulting solution was stirred for the appropriate time (see Table 1 and Scheme 2) at that temperature. Sat. aq NH4Cl was added (2 mL/mmol substrate) and the cooling bath was removed, the mixture was stirred till it reached r.t., and then it was extracted with additional Et2O (2 × 5 mL) and washed with water (5 mL) and brine (10 mL). The organic phase was dried (anhyd Na2SO4), filtered, and the solvent removed under reduced pressure to give pure samples of haloacetamides.
 

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