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Chemical Structure| 45584-07-4 Chemical Structure| 45584-07-4

Structure of 45584-07-4

Chemical Structure| 45584-07-4

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Product Details of [ 45584-07-4 ]

CAS No. :45584-07-4
Formula : C6H14N2
M.W : 114.19
SMILES Code : CNC1CCNCC1
MDL No. :MFCD00078349

Safety of [ 45584-07-4 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H314
Precautionary Statements:P280-P305+P351+P338-P310
Class:8
UN#:2735
Packing Group:

Application In Synthesis of [ 45584-07-4 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 45584-07-4 ]

[ 45584-07-4 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 45584-07-4 ]
  • [ 84946-20-3 ]
  • [ 108635-83-2 ]
YieldReaction ConditionsOperation in experiment
With potassium carbonate; In i-Amyl alcohol; water; Petroleum ether; 1.2. 1-{1-[(4-Fluorophenyl)methyl]-1H-benzimidazol-2-yl}-N-methyl-4-piperidinamine (method B) 8.7 g (0.05 mole) of 4-methylaminopiperidine (in the form of acetate), 13 g (0.05 mole) of 1-(4-fluorobenzyl)-2-chlorobenzimidazole and 13.8 g (0.1 mole) of potassium carbonate in 250 ml of isoamyl alcohol are brought to reflux temperature for 192 h. The mixture is cooled and evaporated to dryness. The residue is taken up with a mixture of water and ether and agitated until crystallization occurs. The compound (V) obtained in hydrate form is filtered off. The precipitate is taken up with toluene and agitated until dissolution has occurred, and the solution is dried with magnesium sulphate, filtered and evaporated. The residual oil is ground in petroleum ether. The solid product is filtered off and dried. The compound thereby obtained melts at 77-80 C.
 

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