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Chemical Structure| 4482-01-3 Chemical Structure| 4482-01-3

Structure of 4482-01-3

Chemical Structure| 4482-01-3

Benzo[d][1,3,2]dithiazole 1,1,3,3-tetraoxide

CAS No.: 4482-01-3

4.5 *For Research Use Only !

Cat. No.: A665759 Purity: 98%

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Product Details of [ 4482-01-3 ]

CAS No. :4482-01-3
Formula : C6H5NO4S2
M.W : 219.24
SMILES Code : O=S1(NS(C2=CC=CC=C21)(=O)=O)=O
MDL No. :MFCD07779379

Safety of [ 4482-01-3 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319
Precautionary Statements:P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313

Application In Synthesis of [ 4482-01-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 4482-01-3 ]

[ 4482-01-3 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 15676-66-1 ]
  • p-nitrobenzenediazonium o-benzenedisulfonimide [ No CAS ]
  • [ 4482-01-3 ]
  • [ 58259-34-0 ]
  • 2
  • [ 4482-01-3 ]
  • [ 87199-17-5 ]
  • [ 106-40-1 ]
  • [ 50670-58-1 ]
YieldReaction ConditionsOperation in experiment
87% General procedure: In a oven-dried flask and under nitrogen flow, benzenediazonium o-benzenedisulfonimide (1a, 161mg, 0.5mmol) was added to a suspension of 4-methoxyphenylboronic acid (3a, 91mg, 0.6mmol), [bis(trifluoromethanesulfonyl)imidate](triphenylphosphine)gold(I) (2:1) toluene adduct (39mg, 0.025mmol, 5mol%), Cs2CO3 (325mg, 1mmol) in THF (5mL). The resulting mixture was stirred at room temperature for 2h; the completion of the reaction was confirmed by the absence of azo coupling with 2-naphthol. Then, the reaction mixture was poured into diethyl ether/water (100mL, 1:1). The aqueous layer was separated and extracted with diethyl ether (50mL). The combined organic extracts were washed with water (50mL), dried with Na2SO4 and evaporated under reduced pressure. GC-MS analyses of the crude residue showed 4-methoxybiphenyl (4a), MS (EI): m/z 184 (M+) as the major product, besides traces of biphenyl, MS (EI): m/z 154 (M+), 4,4'-dimethoxybiphenyl, MS (EI): m/z 214 (M+), N-phenyl-o-benzenedisulfonimide, MS (EI): m/z 295 (M+). The crude residue was purified on a short column, eluting with petroleum ether/diethyl ether (9:1). The only isolated product was the title compound (4a, 81mg, 88% yield).
 

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