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Chemical Structure| 42310-45-2 Chemical Structure| 42310-45-2

Structure of 42310-45-2

Chemical Structure| 42310-45-2

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Product Details of [ 42310-45-2 ]

CAS No. :42310-45-2
Formula : C5H8N4O
M.W : 140.14
SMILES Code : NC1=NC=C(CO)C(N)=N1
MDL No. :MFCD06410821

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* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 42310-45-2 ]

[ 42310-45-2 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 42310-45-2 ]
  • [ 16462-27-4 ]
  • [ 2734-70-5 ]
  • [ 56066-19-4 ]
YieldReaction ConditionsOperation in experiment
With hydrogenchloride; acetic acid; In water; EXAMPLE 11 Preparation of 2,4-Diamino-5-(4-amino-3,5-dimethoxybenzyl)pyrimidine A mixture of 2,4-diamino-5-hydroxymethylpyrimidine (4.30 g, 30.0 mmol), prepared from 2,4-diamino-5-cyanopyrimidine as described in U.K. Pat. No. 1 413 472, <strong>[2734-70-5]2,6-dimethoxyaniline</strong> (5.05 g, 33.0 mmol), acetic acid (60 mL), and concentrated hydrochloric acid (4.2 mL) was refluxed for 41/2 hours, cooled, and filtered to give the hydrochloride salt of the title compound (7.13 g, 76.2%). The salt was dissolved in water and the solution made basic with concentrated ammonium hydroxide. The resulting precipitate was filtered, washed with water, and dried to give the title compound (5.18 g, 62.7%). Calculated for C13 H17 N5 O2: C, 56.72; H, 6.22; N, 25.44. Found: C, 56.63; H, 6.29; N, 25.39.
 

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