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Chemical Structure| 41507-35-1 Chemical Structure| 41507-35-1

Structure of 41507-35-1

Chemical Structure| 41507-35-1

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Product Details of [ 41507-35-1 ]

CAS No. :41507-35-1
Formula : C5H3ClOS
M.W : 146.59
SMILES Code : O=C(Cl)C1=CSC=C1
MDL No. :MFCD00130090
InChI Key :QTWBEVAYYDZLQL-UHFFFAOYSA-N
Pubchem ID :2776377

Safety of [ 41507-35-1 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H228-H314
Precautionary Statements:P210-P240-P241-P260-P264-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P321-P363-P370+P378-P405-P501
Class:8(4.1)
UN#:2921
Packing Group:

Application In Synthesis of [ 41507-35-1 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 41507-35-1 ]

[ 41507-35-1 ] Synthesis Path-Downstream   1~5

  • 1
  • [ 41507-35-1 ]
  • [ 456-00-8 ]
  • [ 99923-42-9 ]
  • 2
  • [ 41507-35-1 ]
  • [ 4949-69-3 ]
  • [ 623907-55-1 ]
YieldReaction ConditionsOperation in experiment
With pyridine; potassium carbonate; In dichloromethane; at 0 - 20℃; for 19h; Example 7; N-(3-{8-(2.6-DifluorophenylV7-oxo-2-r(2,2,6.6-tetramethyl-4-piperidinyl')aminol-5,6,7, 8-tetrahydropyrimido[4,5-(/1pyrimidin-4-yl|-4-methylphenyl)-3- thiophenecarboxamide; 7a) N-Q -iodo-4-methyrphenyl)-3 -thiophenecarboxamide; 3-Thiophenecarboxylic acid (2.O g, 15.6 mmol) was dissolved in methylene chloride (100 mL) and 2 drops of DMF were added. The mixture was cooled to 0 0C and oxalyl chloride (1.5 mL, 17.1 mmol) was added slowly and allowed to warm to room temperature. Gas evolution was observed during warming. 3-Methyl-4- iodoaniline (5.45 g, 23.5 mmol), 4 drops of pyridine and K2CO3 (2.58 g, 18.7 mmol) are dissolved in CH2Cl2 (10 mL) and cooled to about 00C. After about Ih, the acid chloride mixture is slowly added to the cooled aniline mixture and allowed to warm to room temperature and stirred for about 18h. The resulting mixture is filtered, washed with ethyl acetate and the filtrate is concentrated to a brown oil. The crude EPO <DP n="125"/>material was purified via flash chromatography (10-30% ethyl acetate in hexanes) to afford the title compound (1.56 g, 29%) as an off-white solid.
  • 3
  • [ 41507-35-1 ]
  • [ 718632-46-3 ]
  • C20H26N4O5S [ No CAS ]
  • 4
  • [ 41507-35-1 ]
  • [ 1081-04-5 ]
  • [ 1448314-57-5 ]
  • 5
  • [ 41507-35-1 ]
  • [ 27757-86-4 ]
 

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