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Chemical Structure| 40281-50-3 Chemical Structure| 40281-50-3

Structure of 40281-50-3

Chemical Structure| 40281-50-3

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Product Details of [ 40281-50-3 ]

CAS No. :40281-50-3
Formula : C14H11FO
M.W : 214.24
SMILES Code : FC1=CC(C(CC2=CC=CC=C2)=O)=CC=C1
MDL No. :MFCD02260663
Boiling Point : No data available

Safety of [ 40281-50-3 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H332-H335
Precautionary Statements:P261-P264-P270-P271-P280-P301+P312+P330-P302+P352-P304+P340+P312-P305+P351+P338-P332+P313-P337+P313-P362-P403+P233-P405-P501

Application In Synthesis of [ 40281-50-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 40281-50-3 ]

[ 40281-50-3 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 178686-24-3 ]
  • [ 40281-50-3 ]
  • [ 57-13-6 ]
  • [ 1283117-41-8 ]
YieldReaction ConditionsOperation in experiment
13% With hydrogenchloride; In ethanol; water;Reflux; 00177] A mixture of l-(3-fluorophenyl)-2-phenylethanone (100 mg, 0.47 mmol), 3- ethoxy-4-hydroxy-5-nitrobenzaldehyde (82 mg, 0.39 mmol), urea (70 mg, 1.17 mmol), and concentrated HC1 solution (0.03 mL, 0.39 mmol) in EtOH (5 mL) was refluxed overnight. The mixture was evaporated in vacuo and purified by preparative HPLC to give Compound 32 (22.35 mg, yield 13%) as a yellow solid. 1H NMR (DMSO-d6 400 MHz): delta 10.28 (s, IH), 8.79 (s, IH), 7.56 (s, IH), 7.42 (s, IH), 7.30-7.25 (m, IH), 7.16 (s, IH), 7.12-6.99 (m, 6H), 6.86 (d, J = 1.6 Hz, 2H), 5.23 (d, J = 2.4 Hz, IH), 4.04 (q, J = 7.2 Hz, 2H), 1.33 (t, J = 1.2 Hz, 3H); MS (ESI): m/z 450.0 [M+l]+.
 

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