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Chemical Structure| 40222-77-3 Chemical Structure| 40222-77-3
Chemical Structure| 40222-77-3

2-Hydroxymethyl-5-hydroxypyridine

CAS No.: 40222-77-3

Synonyms: 2-Hydroxymethyl-5-hydroxypyridine

4.5 *For Research Use Only !

Cat. No.: A203469 Purity: 95%

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Product Details of 2-Hydroxymethyl-5-hydroxypyridine

CAS No. :40222-77-3
Formula : C6H7NO2
M.W : 125.13
SMILES Code : OC1=CC=C(CO)N=C1
Synonyms :
2-Hydroxymethyl-5-hydroxypyridine
MDL No. :MFCD16249568
InChI Key :NESFDGDRYVANBC-UHFFFAOYSA-N
Pubchem ID :419490

Safety of 2-Hydroxymethyl-5-hydroxypyridine

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H332-H335
Precautionary Statements:P280-P305+P351+P338-P310

Application In Synthesis of 2-Hydroxymethyl-5-hydroxypyridine

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 40222-77-3 ]

[ 40222-77-3 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 40222-77-3 ]
  • [ 31191-08-9 ]
YieldReaction ConditionsOperation in experiment
60% With manganese(IV) oxide; In isopropyl alcohol; at 85℃; for 2h; An activated MnO2 (2.5 times more in weight) was added to the 6-(hydroxymethyl)pyridin-3-ol and the reactants were suspended in i-PrOH The reaction mixture was refluxed for 2 h (the boiling should not significantly exceed this time), after which it was cooled down and filtered. The resulting turbid dark solution was centrifuged and carefully decanted. The pure product could be obtained by recrystallization from boiling water as a brown crystalline solid. Yield 2.9 g (60 %). 1H NMR (400MHz, DMSO-d6 ): delta 11.10 (s, 1 H); 9.83 (s, 1 H); 8.32 (d, J = 2.2, 1 H); 7.85 (d, J = 9.5, 1 H); 7.33 (dd, J = 2.1, J = 8.6, 1 H);
 

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