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Chemical Structure| 39718-32-6 Chemical Structure| 39718-32-6
Chemical Structure| 39718-32-6

1,4-Difluoro-2-isocyanatobenzene

CAS No.: 39718-32-6

4.5 *For Research Use Only !

Cat. No.: A400033 Purity: 98%

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Product Details of [ 39718-32-6 ]

CAS No. :39718-32-6
Formula : C7H3F2NO
M.W : 155.10
SMILES Code : O=C=NC1=CC(F)=CC=C1F
MDL No. :MFCD00013843
InChI Key :SNHIIFOXCRYGGY-UHFFFAOYSA-N
Pubchem ID :2733266

Safety of [ 39718-32-6 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H225-H301-H312-H315-H319-H332-H335
Precautionary Statements:P261-P280-P305+P351+P338
Class:6.1(3)
UN#:3080
Packing Group:

Application In Synthesis [ 39718-32-6 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 39718-32-6 ]

[ 39718-32-6 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 845305-83-1 ]
  • [ 39718-32-6 ]
  • [ 1138448-35-7 ]
YieldReaction ConditionsOperation in experiment
With triethylamine; In dichloromethane; at 20℃; for 18h; Compound IB (200 mg, 0.704 mmol) was dissolved in 10 mL Of CH2Cl2. Triethylamine (213 mg, 2.112 mmol) was added followed by 2,5-difluorophenylisocyanate (328 mg, 2.112 mmol) and the resulting reaction was stirred at room temperature for 18 hours. The reaction mixture was then diluted with CH2Cl2, washed with a IN NaOH aqueous solution, and the organic layer was dried over sodium sulfate and concentrated in vacuo. The residue obtained was purified using flash column chromatography (EtOAc/Hexanes, 1 :2) to provide compound 5A as a yellow oil.
 

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