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Chemical Structure| 394222-91-4 Chemical Structure| 394222-91-4

Structure of 394222-91-4

Chemical Structure| 394222-91-4

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Product Details of [ 394222-91-4 ]

CAS No. :394222-91-4
Formula : C8H7F2N3
M.W : 183.16
SMILES Code : NCC1=NC2=C(F)C=C(F)C=C2N1

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Application In Synthesis of [ 394222-91-4 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 394222-91-4 ]

[ 394222-91-4 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 2369-29-1 ]
  • [ 56-40-6 ]
  • [ 394222-91-4 ]
YieldReaction ConditionsOperation in experiment
With sodium carbonate; In hydrogenchloride; chloroform; (a) (4,6-Difluoro-1H-benzimidazol-2-yl)-methylamine A mixture of glycine (2.0 g) and 3,5-difluoro-benzene-1,2-diamine in 5M hydrochloric acid (5 mL) was heated under reflux for 18 hours and evaporated. Sodium carbonate solution was added to pH 10 and the solution was extracted with dichloromethane. The aqueous fraction was evaporated to dryness and the residue was extracted with 5% methanol in chloroform, dried and evaporated to give a foam (0.6 g). MS (+ve ion electrospray) m/z 184 (MH+).
 

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