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Chemical Structure| 394-64-9 Chemical Structure| 394-64-9

Structure of 394-64-9

Chemical Structure| 394-64-9

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Product Details of [ 394-64-9 ]

CAS No. :394-64-9
Formula : C8H9FO2
M.W : 156.15
SMILES Code : COC1=C(OC)C(F)=CC=C1
MDL No. :MFCD03411451
InChI Key :MNBADDMXGOBTIC-UHFFFAOYSA-N
Pubchem ID :2758979

Safety of [ 394-64-9 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H320-H335
Precautionary Statements:P264-P270-P301+P312-P330

Application In Synthesis of [ 394-64-9 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 394-64-9 ]

[ 394-64-9 ] Synthesis Path-Downstream   1~3

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  • [ 363-52-0 ]
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  • [ 74-88-4 ]
  • [ 394-64-9 ]
YieldReaction ConditionsOperation in experiment
93% With potassium carbonate; In DMF (N,N-dimethyl-formamide); at 0 - 20℃; for 18h; After dissolving the starting material (30 g, 0.234 mol) in dimethylformamide (400 ml), methyl iodide (32 ml, 0.515 mol) and potassium carbonate (80.7 g, 0.515 mol) were added while stirring on ice, and the stirring was continued at room temperature for 18 hours. Water (500 ml) was added and extraction was performed with diethyl ether (400 ml x 2), and then after washing the combined organic layers with brine (400 ml) and drying over anhydrous magnesium sulfate, the solvent was distilled off under reduced pressure to yield the title compound as a light yellow liquid (34 g, 93percent).1H-NMR(CDCl3)delta(ppm) 3.86(3H,s), 3.92(3H,s), 6.65-6.98(3H,m).
  • 3
  • [ 363-52-0 ]
  • [ 77-78-1 ]
  • [ 394-64-9 ]
 

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