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Chemical Structure| 391248-13-8 Chemical Structure| 391248-13-8

Structure of 391248-13-8

Chemical Structure| 391248-13-8

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Product Details of [ 391248-13-8 ]

CAS No. :391248-13-8
Formula : C9H18N2O2S
M.W : 218.32
SMILES Code : O=C(N1CSC[C@H]1CN)OC(C)(C)C
MDL No. :MFCD02683053

Safety of [ 391248-13-8 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319-H335
Precautionary Statements:P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P362-P403+P233-P501

Application In Synthesis of [ 391248-13-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 391248-13-8 ]

[ 391248-13-8 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 391248-13-8 ]
  • [ 166599-84-4 ]
  • [ 1061591-40-9 ]
YieldReaction ConditionsOperation in experiment
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; A.4.1 Synthesis of 4-[acyl-amino]-methyl}-thiazolidine-3-carboxylic acid tert-butyl ester Derivatives (General Procedure)To a solution of the respective carboxylic acid R1COOH, wherein R1 is as defined for formula (I), (4.6 mmol, 1.0 eq.), 4-aminomethyl-thiazolidine-3-carboxylic acid tert-butyl ester (4.6 mmol, 1.0 eq.) and DMAP (2.3 mmol, 1.0 eq.) in DCM (25 mL) was added under stirring solid EDC (4.7 mmol, 1.02 eq.). Stirring continued over night. Then sat. aq. NaHCO3 solution (6 mL) was added to the reaction mixture and stirring continued for 30 min. The organic phase was separated, the solvent was stripped off yielding the crude corresponding 4-[acyl-amino]-methyl}-thiazolidine-3-carboxylic acid tert-butyl ester derivative.
 

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