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Structure of 374794-89-5

Chemical Structure| 374794-89-5

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Product Details of [ 374794-89-5 ]

CAS No. :374794-89-5
Formula : C13H23NO3
M.W : 241.33
SMILES Code : O=C(N(CC1)CCC21CCCO2)OC(C)(C)C
MDL No. :MFCD11042293
InChI Key :JLIBXBGSIZHAPD-UHFFFAOYSA-N
Pubchem ID :21955197

Safety of [ 374794-89-5 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P280-P301+P312-P302+P352-P305+P351+P338

Application In Synthesis of [ 374794-89-5 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 374794-89-5 ]

[ 374794-89-5 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 374794-89-5 ]
  • [ 3970-79-4 ]
YieldReaction ConditionsOperation in experiment
98% With hydrogenchloride; In methanol; at 20℃; for 3.0h; Methanolic hydrogen chloride (3M, 20 mL) was added over 10 minutes to a stirred, cooled (0 C.) solution of 1,1-dimethylethyl 1-oxa-8-azaspiro[4,5]decane-8-carboxylate (Description 74, 3.18 g, 13.2 mmol) in methanol (10 mL) and the mixture was stirred at room temperature for 3 hours. The solvent was evaporated under reduced pressure to give the title compound (2.29 g, 98%). m/z (ES+) 142 (M+1).
98% With hydrogenchloride; In methanol; at 0 - 20℃; for 3.0h; Methanolic hydrogen chloride (3M, 20ML) was added over 10 minutes to a stirred, cooled (0C) solution of 1, 1-dimethylethyl l-oxa-8-azaspiro [4. 5] DECANE-8-CARBOXYLATE (from step (iv) above, 3. 18G, 13. 2MMOL) in methanol (10ML) and the mixture was stirred at room temperature for 3 hours. The solvent was evaporated under reduced pressure to give the title compound (2. 29g, 98%). 1H NMR (400 MHz, CDC13) : 8 3. 85 (2H, t, J 7Hz), 3.27-3. 15 (4H, m), 1.98 (2H, QUIN. , J7HZ), 1. 86-1. 75 (6H, M); M/Z (ES+) 142 (M+1).
 

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