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Chemical Structure| 37443-42-8 Chemical Structure| 37443-42-8

Structure of 37443-42-8

Chemical Structure| 37443-42-8

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Product Details of [ 37443-42-8 ]

CAS No. :37443-42-8
Formula : C6H10O3
M.W : 130.14
SMILES Code : O=C(C1OCCC1)OC
MDL No. :MFCD00154541
InChI Key :IXHZGHPQQTXOKV-UHFFFAOYSA-N
Pubchem ID :169922

Safety of [ 37443-42-8 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H226-H315-H318-H335
Precautionary Statements:P210-P233-P240-P241-P242-P243-P261-P264-P271-P280-P303+P361+P353-P304+P340+P312-P305+P351+P338+P310-P332+P313-P362-P370+P378-P403+P233+P235-P405-P501
Class:3
UN#:3271
Packing Group:

Application In Synthesis of [ 37443-42-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 37443-42-8 ]

[ 37443-42-8 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 37443-42-8 ]
  • [ 619329-27-0 ]
YieldReaction ConditionsOperation in experiment
69% With trimethylaluminum; ammonium chloride; In hexane; toluene; at 0 - 80℃; Example 3A; Tetrahydro-2-furancarboximidamide hydrochloride; 41.1 g (768 mmol, 5 equiv.) ammonium chloride are suspended in 400 ml of dry toluene under an argon atmosphere, and the mixture is cooled to 0C. 385 ml (768 mmol, 5 equiv. ) of a 2 M solution of trimethylaluminium in hexane are added dropwise, and the reaction mixture is stirred at room temperature until no more evolution of gas is observed. After addition of 20 g (154 mmol, 1 equiv. ) methyl tetrahydro-2-furancarboxylate, the mixture is stirred at 80C bath temperature over night. It is then cooled down to 0C, and 200 ml of methanol are added with con- sequent stirring for 1 hour at room temperature. After filtration, the solid is washed with methanol for several times and the solution is evaporated to dryness in vacuo. Yield: 15.9 g (69%)
 

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