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Chemical Structure| 371158-46-2 Chemical Structure| 371158-46-2

Structure of 371158-46-2

Chemical Structure| 371158-46-2

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Product Details of [ 371158-46-2 ]

CAS No. :371158-46-2
Formula : C13H20N2O2
M.W : 236.31
SMILES Code : O=C(OC(C)(C)C)NC1=CC(C)=C(C)C=C1N
MDL No. :MFCD17029211

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Application In Synthesis of [ 371158-46-2 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 371158-46-2 ]

[ 371158-46-2 ] Synthesis Path-Downstream   1~3

  • 1
  • [ 1074-12-0 ]
  • [ 182482-25-3 ]
  • [ 371158-46-2 ]
  • [ 1334220-51-7 ]
YieldReaction ConditionsOperation in experiment
24% In dichloromethane; at 120℃; for 0.25h;Microwave irradiation; General procedure: One millimolar of each diamine, glyoxaldehyde and boronic acid were taken into a microwave vial already equipped with a magnetic bar. 1 mL of dichloromethane was added to the system followed by heating it at 120 C for 15 min. The crude Petasis product was then directly loaded to an ISCO purification system and using ethylacetate/hexane as eluent (0-100% gradient over 25 min) the products were purified. A weighed out amount of Petasis product (0.10-0. 30 mmol) was then subjected to 1-2 mL of 20% TFA in dichloromethane. The reaction was stirred for 18 h at room temperature, evaporated in vacuo and crude material purified via chromatography (ISCO) to afford the desired product (77% yield) as a white solid.
  • 2
  • [ 1074-12-0 ]
  • [ 182482-25-3 ]
  • [ 371158-46-2 ]
  • [ 1334220-61-9 ]
  • 3
  • [ 1074-12-0 ]
  • [ 1029649-48-6 ]
  • [ 7194-78-7 ]
  • [ 371158-46-2 ]
  • C41H43BrN4O8 [ No CAS ]
 

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