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Chemical Structure| 364793-82-8 Chemical Structure| 364793-82-8

Structure of 364793-82-8

Chemical Structure| 364793-82-8

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Product Details of [ 364793-82-8 ]

CAS No. :364793-82-8
Formula : C11H14BrNO
M.W : 256.14
SMILES Code : BrC1=CC(CN2CCOCC2)=CC=C1
MDL No. :MFCD00979456
InChI Key :DQGAMPWGTUCNGP-UHFFFAOYSA-N
Pubchem ID :783082

Safety of [ 364793-82-8 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P280-P301+P312-P302+P352-P305+P351+P338

Application In Synthesis of [ 364793-82-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 364793-82-8 ]

[ 364793-82-8 ] Synthesis Path-Downstream   1~2

  • 2
  • [ 73183-34-3 ]
  • [ 364793-82-8 ]
  • 4-(2,4-Dichloro-5-methoxyanilino)-7-[3-(4-morholinylmethyl) phenyll-3-quinolinecarbonitrile [ No CAS ]
  • [ 364794-80-9 ]
YieldReaction ConditionsOperation in experiment
With potassium acetate; In water; dimethyl sulfoxide; ethyl acetate; toluene; EXAMPLE 26 4-(2,4-Dichloro-5-methoxyanilino)-7-[3-(4-morholinylmethyl) phenyll-3-quinolinecarbonitrile To a dry flask under a nitrogen atmosphere was added 200 mg (0.78 mmol) of 4-(3-bromobenzyl) morpholine, 0.218 g (0.86 mmol) of bis(pinacolato) diboron, 230 mg (2.34 mmol) of potassium acetate, 5 mL of dimethylsulfoxide and 32 mg (0.04 mmol) of [1,1'-bis(diphenylphosphino) ferrocene]dichloropalladium(II), complex with dichloromethane. The reaction mixture was heated at 80 C. for 2 hours. After cooling, the mixture was partitioned between 20 mL of toluene, 40 mL of ethyl acetate and 40 mL of water. The layers were separated and the aqueous layer was further extracted with 30 mL of ethyl acetate. The organic layers were combined and washed with 4*40 mL water. After drying over magnesium sulfate, removal of the solvents gave crude 4-[3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl) benzyl]morpholine as a dark oil.
 

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