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Chemical Structure| 3622-47-7 Chemical Structure| 3622-47-7

Structure of 3622-47-7

Chemical Structure| 3622-47-7

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Product Details of [ 3622-47-7 ]

CAS No. :3622-47-7
Formula : C7H3ClINS
M.W : 295.53
SMILES Code : IC1SC2C(=CC=C(C=2)Cl)N=1

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Application In Synthesis of [ 3622-47-7 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 3622-47-7 ]

[ 3622-47-7 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 3622-47-7 ]
  • [ 943443-12-7 ]
  • 4-chloro-2-(6-chlorobenzothiazol-2-yl)benzoxazole [ No CAS ]
YieldReaction ConditionsOperation in experiment
19% With 1,10-Phenanthroline; nickel dichloride; lithium tert-butoxide; In 1,4-dioxane; at 90℃;Inert atmosphere; Under a nitrogen atmosphere, the compound obtained in d) (296 mg, 1.0 mmol), nickel chloride (1.3 mg), 1,10-phenanthroline (1.8 mg), and lithium t-butoxide (160 mg, 2.0 mmol) were added to a solution of the compound obtained in c) (184 mg, 1.2 mmol) in 1,4-dioxane (4 mL), and the resulting mixture was stirred overnight with heating at 90 C. The reaction mixture was left to cool to room temperature, the insoluble matter was removed by using Celite, the filtrate was evaporated under reduced pressure, and the resulting residue was purified by silica gel column chromatography to obtain crystals of the title compound (60 mg, yield 19%). 1H-NMR (DMSO-d6) δ: 7.6-7.7 (3H, m), 7.9-8.0 (1H, m), 8.26 (1H, d, J=8.9 Hz), 8.4-8.5 (1H, m)Melting point: 268.2 C.
 

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