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Chemical Structure| 35717-98-7 Chemical Structure| 35717-98-7

Structure of 35717-98-7

Chemical Structure| 35717-98-7

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Product Details of [ 35717-98-7 ]

CAS No. :35717-98-7
Formula : C14H23O6PS
M.W : 350.37
SMILES Code : O=S(C1=CC=C(C)C=C1)(OCP(OC(C)C)(OC(C)C)=O)=O
MDL No. :MFCD06660915

Safety of [ 35717-98-7 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P330-P332+P313-P337+P313-P362-P403+P233-P405-P501

Application In Synthesis of [ 35717-98-7 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 35717-98-7 ]

[ 35717-98-7 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 35717-98-7 ]
  • [ 122794-99-4 ]
  • [ 1389323-22-1 ]
YieldReaction ConditionsOperation in experiment
35% With potassium carbonate; In N,N-dimethyl-formamide; at 80℃; for 48h; General procedure: The appropriate oxoquinoline derivative 5 (1.75 mmol) was stirred for 15 minutes in the presence of 750.0 mg of K2CO3 and 5.0mL of DMF, followed by the addition of diisopropyl(tosylmethoxy)phosphonate 4 (3.50 mmol). The reaction mixture was additionally stirred for 48 h at 80 C. Afterwards, the resulting mixture was poured into water (30 mL) and extracted with methylene chloride (3 x 20 mL). The combined organic extracts were washed with water (3 x 20 mL), dried over anhydrous magnesium sulfate, filtered and evaporated, giving rise to ethyl 1-[(diisopropoxyphosphoryl)methyl]-4-oxo-1,4-dihydroquinoline-3-carboxylates 3a-3k which were purified by crystallization from ethyl ether.
  • 2
  • [ 35717-98-7 ]
  • [ 208580-23-8 ]
  • [ 1389323-23-2 ]
YieldReaction ConditionsOperation in experiment
34% With potassium carbonate; In N,N-dimethyl-formamide; at 80℃; for 48h; General procedure: The appropriate oxoquinoline derivative 5 (1.75 mmol) was stirred for 15 minutes in the presence of 750.0 mg of K2CO3 and 5.0mL of DMF, followed by the addition of diisopropyl(tosylmethoxy)phosphonate 4 (3.50 mmol). The reaction mixture was additionally stirred for 48 h at 80 C. Afterwards, the resulting mixture was poured into water (30 mL) and extracted with methylene chloride (3 x 20 mL). The combined organic extracts were washed with water (3 x 20 mL), dried over anhydrous magnesium sulfate, filtered and evaporated, giving rise to ethyl 1-[(diisopropoxyphosphoryl)methyl]-4-oxo-1,4-dihydroquinoline-3-carboxylates 3a-3k which were purified by crystallization from ethyl ether.
 

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