Home Cart Sign in  
Chemical Structure| 340714-55-8 Chemical Structure| 340714-55-8

Structure of 340714-55-8

Chemical Structure| 340714-55-8

*Storage: {[sel_prStorage]}

*Shipping: {[sel_prShipping]}

,{[proInfo.pro_purity]}

4.5 *For Research Use Only !

{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

Change View

Size Price VIP Price

US Stock

Global Stock

In Stock
{[ item.pr_size ]} Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

  • {[ item.pr_size ]}

In Stock

- +

Please Login or Create an Account to: See VIP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

  • 1-2 Day Shipping
  • High Quality
  • Technical Support
Product Citations

Alternative Products

Product Details of [ 340714-55-8 ]

CAS No. :340714-55-8
Formula : C21H17F6NO4
M.W : 461.35
SMILES Code : O=C([C@H](CC(C(F)(F)F)C(F)(F)F)NC(=O)OCC1C2C=CC=CC=2C2C=CC=CC1=2)O
MDL No. :N/A

Safety of [ 340714-55-8 ]

Application In Synthesis of [ 340714-55-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 340714-55-8 ]

[ 340714-55-8 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 17114-97-5 ]
  • [ 340714-55-8 ]
  • 3-<i>tert</i>-butoxy-2-(2-<i>tert</i>-butoxycarbonylamino-5,5,5-trifluoro-4-trifluoromethyl-pentanoylamino)-propionic acid methyl ester [ No CAS ]
YieldReaction ConditionsOperation in experiment
87% With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; In DMF (N,N-dimethyl-formamide); at 20℃; for 0.666667h; To a stirred solution of 5 (11 mg, 0.03 mmol) in anhydrous DMF (1 mL) was added diisopropyl ethyl amine (13 mg, 0.1 mmol), HBTU (13 mg, 0.03 mmol), and H-Ser(t-Bu)-OMe HCl (14 mg, 0.065 mmol) sequentially. The mixture was stirred at room temperature for 40 min before 6 mL of H2O was added. The reaction mixture was extracted with ether (15 ml) and the organic layer was futher washed with 1 N HCl (5 mL.x.2) and 5percent NaHCO3 solution (5 ml), dried over MgSO4, and concentrated to afford 8 (13 mg, 87percent yield) as a white solid. 1H NMR (300 MHz, CDCl3) delta 6.68 (d, 1H, J=8.1 Hz), 5.21 (d, 1H, J=8.1 Hz), 4.64 (m, 1H), 4.40 (m, 1H), 3.86 (dd, 1H, J=2.7 Hz, 9.3 Hz), 3.76 (s, 3H), 3.56 (dd, 1H, J=3.3 Hz, 9.3 Hz), 3.50 (m, 1H), 2.33-2.10 (br. m, 2H), 1.45 (s, 9H), 1.14 (s, 9H).
 

Historical Records