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Chemical Structure| 33538-10-2 Chemical Structure| 33538-10-2

Structure of 33538-10-2

Chemical Structure| 33538-10-2

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Product Details of [ 33538-10-2 ]

CAS No. :33538-10-2
Formula : C9H10N2
M.W : 146.19
SMILES Code : N#CC1=CC(C(C)C)=NC=C1
MDL No. :MFCD18384684

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Application In Synthesis of [ 33538-10-2 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 33538-10-2 ]

[ 33538-10-2 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 33538-10-2 ]
  • [ 191535-55-4 ]
YieldReaction ConditionsOperation in experiment
Reference Example 27 2-Isopropylisonicotinic acid A 7.5 ml portion of 8 N aqueous potassium hydroxide was added to 50 ml of ethanol solution containing 2.7 g of 4-cyano-2-isopropylpyridine, and the mixture was heated under reflux for 12 hours.. After cooling to room temperature, the reaction mixture was mixed with water and diethyl ether and the aqueous layer was separated.. The aqueous layer was adjusted to an acidic PH of 3 using 4 N hydrochloric acid and then saturated with sodium chloride.. This was extracted with a mixed solvent of ethyl acetate-isopropanol (5:1, v/v) and dried over anhydrous magnesium sulfate, and then the solvent was evaporated under reduced pressure to obtain 3.1 g of the title compound.
  • 2
  • aqueous potassium hydroxide [ No CAS ]
  • ethyl acetate-isopropanol [ No CAS ]
  • [ 33538-10-2 ]
  • [ 191535-55-4 ]
YieldReaction ConditionsOperation in experiment
With hydrogenchloride; In ethanol; water; Reference Example 27 2-Isopropylisonicotinic acid A 7.5 ml portion of 8 N aqueous potassium hydroxide was added to 50 ml of ethanol solution containing 2.7 g of 4-cyano-2-isopropylpyridine, and the mixture was heated under reflux for 12 hours. After cooling to room temperature, the reaction mixture was mixed with water and diethyl ether and the aqueous layer was separated. The aqueous layer was adjusted to an acidic pH of 3 using 4 N hydrochloric acid and then saturated with sodium chloride. This was extracted with a mixed solvent of ethyl acetate-isopropanol (5:1, v/v) and dried over anhydrous magnesium sulfate, and then the solvent was evaporated under reduced pressure to obtain 3.1 g of the title compound.
 

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