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Chemical Structure| 3159-07-7 Chemical Structure| 3159-07-7
Chemical Structure| 3159-07-7

Quetiapine Related Compound G

CAS No.: 3159-07-7

4.5 *For Research Use Only !

Cat. No.: A161851 Purity: 98%

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Product Details of Quetiapine Related Compound G

CAS No. :3159-07-7
Formula : C13H9NOS
M.W : 227.28
SMILES Code : C1=CC=CC2=C1C(NC3=C(S2)C=CC=C3)=O
MDL No. :MFCD00901197
InChI Key :RTERDTBXBYNZIS-UHFFFAOYSA-N
Pubchem ID :374829

Safety of Quetiapine Related Compound G

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of Quetiapine Related Compound G

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 3159-07-7 ]

[ 3159-07-7 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 3159-07-7 ]
  • [ 17329-87-2 ]
  • 2-(11-oxodibenzo[b,f][1,4]thiazepin-10(11H)-yl)-N-(4-nitrophenyl)acetamide [ No CAS ]
YieldReaction ConditionsOperation in experiment
74% General procedure: In a 250 mLround bottom flask, dibenzo[b,f][1,4]thiazepin-11(10H)-one (1.0 mol) in 25 mLdimethyl formamide at -5C to 0C was added. Sodium hydride (2.5 mol, 60 % w/w) was lot wise added in reaction mixture at -5C to 0C within 25 min. The temperature of reaction mixture was maintained at -5C to 0C for 30 min. Addition of 2-chloro N-phenylacetamide solution (1.2 mol) (I1-13) in reaction mixture within 30 min at -5C to 0C was completed. The temperature of reaction mixture was maintained at 25C to 30C for 12-15 hr. The reaction mixture was poured into crushed ice, filtered, dried and crystallized from ethyl acetate. Similarly other compounds were prepared by using dibenzo[b,f][1,4]thiazepin-11(10H)-one 4 and various N-chlorosubstituted phenylacetamide (I1-13). The synthesized compounds were recrystallized in ethyl acetate. Practical yield and physicochemical parameter are reported below.
 

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