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Chemical Structure| 315-12-8 Chemical Structure| 315-12-8

Structure of 315-12-8

Chemical Structure| 315-12-8

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Product Details of [ 315-12-8 ]

CAS No. :315-12-8
Formula : C8H8FNO2
M.W : 169.15
SMILES Code : CC1=CC(F)=CC(C)=C1[N+]([O-])=O
MDL No. :MFCD03413407
InChI Key :KDPQDERPJHLWGF-UHFFFAOYSA-N
Pubchem ID :12651353

Safety of [ 315-12-8 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H332-H335
Precautionary Statements:P280-P305+P351+P338-P310

Application In Synthesis of [ 315-12-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 315-12-8 ]

[ 315-12-8 ] Synthesis Path-Downstream   1~3

  • 2
  • [ 461-97-2 ]
  • [ 315-12-8 ]
YieldReaction ConditionsOperation in experiment
83% With nitric acid; at -15 - 20℃; for 4h; 1 (6 g, 48.3 mmol, 1 eq) was cooled to -10 ° C and nitric acid (9 g, 143.78 mmol, 3 eq) was added drop wise for 20 min. The mixture was stirred at -15 DEG C for 1 hour, then carefully brought to room temperature and kept stirring for 3 hours. The mixture was poured into ice to give a yellow precipitate, which was filtered and then the filter cake was dissolved in DCM. The organic phase was washed with brine, dried over Na2SO4 and concentrated to give the desired product 2 as a white powder (6.8 g, 83percent yield).
 

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