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Chemical Structure| 31383-81-0 Chemical Structure| 31383-81-0

Structure of 31383-81-0

Chemical Structure| 31383-81-0

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Product Details of [ 31383-81-0 ]

CAS No. :31383-81-0
Formula : C17H18N2O4
M.W : 314.34
SMILES Code : NC1=CC=C(CC2=CC=C(N)C(C(OC)=O)=C2)C=C1C(OC)=O
MDL No. :MFCD00393444

Safety of [ 31383-81-0 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H317-H319
Precautionary Statements:P280-P305+P351+P338

Application In Synthesis of [ 31383-81-0 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 31383-81-0 ]

[ 31383-81-0 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 156150-67-3 ]
  • [ 31383-81-0 ]
  • [ 1056452-45-9 ]
  • [ 1056452-44-8 ]
YieldReaction ConditionsOperation in experiment
27% A mixture of compound IV (0.314 g, 1 mmol), copper(l)tris(triphenyl- phosphine)bromide (372 mg, 0.4 mmol), Cs2CO3 (977 mg, 3 mmol), and toluene (15 mL) was heated under argon at 110 0C for 5 min. The aryl iodide (2 mmol) was added via syringe and the mixture was stirred at 110 0C for 1-2 days. After cooling, the mixture was filtered through a small pad of silica gel, concentrated and purified by chromatography, furnishing the di-arylated compound as the minor product and the mono-arylated as the major product. The subsequent hydrolysis was carried out in accordance with the procedure described in Method A.
 

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