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Chemical Structure| 29955-26-8 Chemical Structure| 29955-26-8

Structure of 29955-26-8

Chemical Structure| 29955-26-8

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Product Details of [ 29955-26-8 ]

CAS No. :29955-26-8
Formula : C15H14O2
M.W : 226.27
SMILES Code : COC1=CC(CC(C2=CC=CC=C2)=O)=CC=C1
MDL No. :MFCD00446972

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Application In Synthesis of [ 29955-26-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 29955-26-8 ]

[ 29955-26-8 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 178686-24-3 ]
  • [ 29955-26-8 ]
  • [ 57-13-6 ]
  • [ 1283117-29-2 ]
YieldReaction ConditionsOperation in experiment
2.5% With hydrogenchloride; In ethanol; water; for 96.0h;Reflux; 00168] To a solution of 2-(3-methoxyphenyl)-l-phenylethanone (400 mg, 1.77 mmol), <strong>[178686-24-3]3-ethoxy-4-hydroxy-5-nitrobenzaldehyde</strong> (374 mg, 1.77 mmol) and urea (244 mg, 5.31 mmol) in 20 mL of ethanol was added 0.2 mL of concentrated HCl, then the mixture was stirred at reflux for 4 days. After the solvent was removed under reduced pressure, the residue was purified by HPLC (35-65% acetonitrile + 0.1% trifluoroacetic acid in water, over 15 min.) and then purified by thin layer chromatography (PE:EtOAc=l :2) further to give Compound 23 (20 mg, yield 2.5%). 1H NMR (CD3OD 400 MHz): delta 7.43 (s, IH), 7.17 (s, 5H), 6.86-6.82 (m, 2H), 6.48 (d, J=6.4 Hz, IH), 6.40 (d, J=8.0 Hz, IH), 6.30 (s, IH), 5.03 (s, IH), 3.91-3.89 (m, 2H), 3.37 (s, 3H), 1.30 (t, J=7.2 Hz, 3H); MS (ESI): mJz 462.3 [M+l]+.
 

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