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Chemical Structure| 298231-14-8 Chemical Structure| 298231-14-8
Chemical Structure| 298231-14-8

Ethyl 4-(2-chlorophenyl)-2,7,7-trimethyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate

CAS No.: 298231-14-8

4.5 *For Research Use Only !

Cat. No.: A697632 Purity: 97%

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Product Details of [ 298231-14-8 ]

CAS No. :298231-14-8
Formula : C21H24ClNO3
M.W : 373.87
SMILES Code : O=C(C1=C(C)NC2=C(C(CC(C)(C)C2)=O)C1C3=CC=CC=C3Cl)OCC
MDL No. :MFCD00653001

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Application In Synthesis of [ 298231-14-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 298231-14-8 ]

[ 298231-14-8 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 674-82-8 ]
  • [ 64-17-5 ]
  • [ 89-98-5 ]
  • [ 873-95-0 ]
  • [ 298231-14-8 ]
YieldReaction ConditionsOperation in experiment
85% With SBA-15/SO3H; In neat (no solvent); at 60℃; for 0.5h;Green chemistry; General procedure: In this work SBA-15 nanoreactor was synthesized by the procedure reported by Zhao et al. [6a] and then modified with mercaptopropyltrimethoxysilane (MPTMS) and oxidized to the sulfonic acid [6b] nanoparticle using hydrogen peroxide (Fig. 1). A mixture of diketene (3 mmol), aldehyde (1 mmol), enamine (1 mmol) and alcohol (4 mL) and SBA-15/SO3H (0.07 g, ~4 mol%) was reacted under neat conditions for appropriate time (TLC). After that, 20 mL hot EtOH was added to the reaction vessel and, with simple centrifuging, the catalyst was removed as filtrate, washed and then the product recrystallized from hot ethanol. All of the products are synthesized by four-component method and were identified by their physical and spectral data (mp, IR, 1H NMR and 13C NMR).
 

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Technical Information

• Acyl Group Substitution • Alkyl Halide Occurrence • Baeyer-Villiger Oxidation • Barbier Coupling Reaction • Baylis-Hillman Reaction • Bouveault-Blanc Reduction • Bucherer-Bergs Reaction • Catalytic Hydrogenation • Clemmensen Reduction • Complex Metal Hydride Reductions • Corey-Bakshi-Shibata (CBS) Reduction • Corey-Chaykovsky Reaction • Ester Cleavage • Fischer Indole Synthesis • General Reactivity • Grignard Reaction • Henry Nitroaldol Reaction • Hiyama Cross-Coupling Reaction • Horner-Wadsworth-Emmons Reaction • Hydride Reductions • Kinetics of Alkyl Halides • Kumada Cross-Coupling Reaction • Lawesson's Reagent • Leuckart-Wallach Reaction • McMurry Coupling • Meerwein-Ponndorf-Verley Reduction • Passerini Reaction • Paternò-Büchi Reaction • Petasis Reaction • Peterson Olefination • Pictet-Spengler Tetrahydroisoquinoline Synthesis • Preparation of Aldehydes and Ketones • Preparation of Amines • Prins Reaction • Reactions of Aldehydes and Ketones • Reactions of Alkyl Halides with Reducing Metals • Reactions of Amines • Reactions of Benzene and Substituted Benzenes • Reactions with Organometallic Reagents • Reformatsky Reaction • Robinson Annulation • Schlosser Modification of the Wittig Reaction • Schmidt Reaction • Specialized Acylation Reagents-Carbodiimides and Related Reagents • Specialized Acylation Reagents-Ketenes • Stille Coupling • Stobbe Condensation • Substitution and Elimination Reactions of Alkyl Halides • Suzuki Coupling • Tebbe Olefination • Ugi Reaction • Wittig Reaction • Wolff-Kishner Reduction

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