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Chemical Structure| 2972-76-1 Chemical Structure| 2972-76-1

Structure of 2972-76-1

Chemical Structure| 2972-76-1

2-(2,4-Dichlorobenzylidene)malononitrile

CAS No.: 2972-76-1

4.5 *For Research Use Only !

Cat. No.: A491657 Purity: 95%

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Product Details of [ 2972-76-1 ]

CAS No. :2972-76-1
Formula : C10H4Cl2N2
M.W : 223.06
SMILES Code : N#CC(C#N)=CC1=CC=C(Cl)C=C1Cl
MDL No. :MFCD00019785

Safety of [ 2972-76-1 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H301-H311-H331
Precautionary Statements:P261-P264-P270-P271-P280-P302+P352-P304+P340-P310-P330-P361-P403+P233-P405-P501
Class:6.1
UN#:2811
Packing Group:

Application In Synthesis of [ 2972-76-1 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 2972-76-1 ]

[ 2972-76-1 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 2972-76-1 ]
  • [ 145091-87-8 ]
  • [ 297162-27-7 ]
YieldReaction ConditionsOperation in experiment
55% General procedure: Dichloromethane (10 mL) was taken in a round-bottomed flask,into which 1.0 equivalent (1 mmol) of triethylamine and pyrazolonewere poured. The mixture was stirred for 2 min without heating. To this mixture, 1.0 equivalent of corresponding presynthesized benzylidene from malononitrile was added. Then the mixture was agitated for 25-30 min. The reaction was observed by TLC. The desired products appeared as precipitates. The precipitates were washed with water to remove the unreacted pyrazolone to obtain pure products. Melting points were recordedfor crystalline substances.
  • 2
  • [ 67-56-1 ]
  • [ 3528-17-4 ]
  • [ 2972-76-1 ]
  • 4-(2,4-dichlorophenyl)-2-methoxy-5H-thiochromeno[4,3-b]pyridine-3-carbonitrile [ No CAS ]
YieldReaction ConditionsOperation in experiment
73% With sodium; at 25 - 30℃; General procedure: A mixture of equimolar amounts of 2,4-dichlorobenzylidenemalononitrile 3 (5 mmol) and the correspondingketone (4ak, 6af) in the appropriate alcohol (15 ml)containing sodium (0.23 g; 10 mmol) was stirred at room temperature(25e30 C) for the appropriate time (TLC control). Theseparated solid was collected, washed with water and crystallizedfrom a suitable solvent affording the corresponding 5amand 7ai.In case of 5n,o the product was purified by glass plates silica gel(GF254) thin layer chromatography (TLC).
 

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