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Chemical Structure| 29182-93-2 Chemical Structure| 29182-93-2

Structure of 29182-93-2

Chemical Structure| 29182-93-2

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Product Details of [ 29182-93-2 ]

CAS No. :29182-93-2
Formula : C10H10BrNO2
M.W : 256.10
SMILES Code : O=C(NC1=CC=C(C(C)=O)C=C1)CBr
MDL No. :MFCD02974382

Safety of [ 29182-93-2 ]

Application In Synthesis of [ 29182-93-2 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 29182-93-2 ]

[ 29182-93-2 ] Synthesis Path-Downstream   1~3

  • 1
  • [ 852443-61-9 ]
  • [ 29182-93-2 ]
  • N-(4-acetylphenyl)-2-(5-amino-3-(trifluoromethyl)-1H-1,2,4-triazol-1-yl)acetamide [ No CAS ]
YieldReaction ConditionsOperation in experiment
75% With triethylamine; In acetonitrile;Reflux; General procedure: 4.1.1.1. General procedure. An equimolar mixture of compound 3, 7a-c and N-(4-acetylphenyl)-2-bromoacetamide 9 (0.25 g,1 mmol) in acetonitrile (50 ml) and TEA (0.10 g, 1.2 mmol) was heated at reflux for 4-8 h. The reaction mixture was evaporated to dryness. The residue was crystallized from aqueous ethanol affording products 10a-d. 4.1.1.1.1. N-(4-acetylphenyl)-2-(5-amino-3-(trifluoromethyl)-1H-1,2,4-triazol-1-yl)acetamide. (10a). White powder (0.25 g, 75%yield), m. p. 240-242 C, IR (KBr) max (cm1) 3180-3470 (NH,NH2), 1715 (COCH3), 1650 (CONH); 1HNMR (400 MHz, DMSO-d6)d (ppm): 2.54 (s, 3H, CH3), 4.89 (s, 2H, CH2), 6.84 (s, 2H, NH2), 7.67(d, 2H, J 8.8 Hz, Ar-H), 7.93 (d, 2H, J 8.8 Hz, Ar-H), 10.67 (s, 1H,NH); 13C NMR (100 MHz, DMSO-d6) d 26.91, 50.21, 118.91, 121.35,123.20, 125.46, 130.08, 132.50, 143.24, 149.40, 149.78, 158.34,165.43, 197.06; HRMS (ESI) m/z: [M H]- calc 326.0943; found 326.0876 for C13H12F3N5O2.
  • 2
  • [ 29182-93-2 ]
  • [ 4922-98-9 ]
  • N-(4-acetylphenyl)-2-(5-amino-3-phenyl-1H-1,2,4-triazol-1-yl)acetamide [ No CAS ]
YieldReaction ConditionsOperation in experiment
70% With triethylamine; In acetonitrile;Reflux; General procedure: 4.1.1.1. General procedure. An equimolar mixture of compound 3, 7a-c and N-(4-acetylphenyl)-2-bromoacetamide 9 (0.25 g,1 mmol) in acetonitrile (50 ml) and TEA (0.10 g, 1.2 mmol) was heated at reflux for 4-8 h. The reaction mixture was evaporated to dryness. The residue was crystallized from aqueous ethanol affording products 10a-d.
  • 3
  • [ 29182-93-2 ]
  • [ 4922-98-9 ]
  • N-(4-(1-(hydroxyimino)ethylphenyl))-2-(5-amino-3-phenyl-1H-1,2,4-triazol-1-yl)acetamide [ No CAS ]
 

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Technical Information

• Acyl Group Substitution • Alkyl Halide Occurrence • Baeyer-Villiger Oxidation • Barbier Coupling Reaction • Baylis-Hillman Reaction • Bucherer-Bergs Reaction • Buchwald-Hartwig C-N Bond and C-O Bond Formation Reactions • Chan-Lam Coupling Reaction • Clemmensen Reduction • Complex Metal Hydride Reductions • Corey-Bakshi-Shibata (CBS) Reduction • Corey-Chaykovsky Reaction • Fischer Indole Synthesis • General Reactivity • Grignard Reaction • Henry Nitroaldol Reaction • Hiyama Cross-Coupling Reaction • Horner-Wadsworth-Emmons Reaction • Hydride Reductions • Kinetics of Alkyl Halides • Kumada Cross-Coupling Reaction • Lawesson's Reagent • Leuckart-Wallach Reaction • Mannich Reaction • McMurry Coupling • Meerwein-Ponndorf-Verley Reduction • Passerini Reaction • Paternò-Büchi Reaction • Petasis Reaction • Peterson Olefination • Pictet-Spengler Tetrahydroisoquinoline Synthesis • Preparation of Aldehydes and Ketones • Preparation of Amines • Prins Reaction • Reactions of Aldehydes and Ketones • Reactions of Alkyl Halides with Reducing Metals • Reactions of Amines • Reactions of Benzene and Substituted Benzenes • Reactions of Dihalides • Reformatsky Reaction • Robinson Annulation • Schlosser Modification of the Wittig Reaction • Schmidt Reaction • Specialized Acylation Reagents-Carbodiimides and Related Reagents • Specialized Acylation Reagents-Ketenes • Specialized Acylation Reagents-Vilsmeier Reagent • Stille Coupling • Stobbe Condensation • Substitution and Elimination Reactions of Alkyl Halides • Suzuki Coupling • Tebbe Olefination • Ugi Reaction • Wittig Reaction • Wolff-Kishner Reduction

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