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Chemical Structure| 288-48-2 Chemical Structure| 288-48-2

Structure of 288-48-2

Chemical Structure| 288-48-2

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Product Details of [ 288-48-2 ]

CAS No. :288-48-2
Formula : C2H2N2S
M.W : 86.12
SMILES Code : S1N=NC=C1

Safety of [ 288-48-2 ]

Application In Synthesis of [ 288-48-2 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 288-48-2 ]

[ 288-48-2 ] Synthesis Path-Downstream   1~2

  • 2
  • [ 288-48-2 ]
  • [ 5497-76-7 ]
  • [ 37566-39-5 ]
  • N-(2-amino-1,3,4-thiadiazol-5-yl)proline tert-butyl ester [ No CAS ]
YieldReaction ConditionsOperation in experiment
With N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; Preparation 65 N-(2-Amino-1,3,4-thiadiazol-5-yl)proline tert-butyl Ester (X-113) (Refer to Chart X.) According to GP I starting from thiadiazole W-95 (1.00 g), proline tert-butyl ester hydrochloride (1.46 g), DIPEA (2.80 mL) and DMF (10 mL). Purification of the crude by FC (AcOEt/hexanes 1:1?AcOEt) yields ester X-113 as a white powder (0.55 g).
 

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