Home Cart Sign in  
Chemical Structure| 27277-03-8 Chemical Structure| 27277-03-8

Structure of 27277-03-8

Chemical Structure| 27277-03-8

*Storage: {[sel_prStorage]}

*Shipping: {[sel_prShipping]}

,{[proInfo.pro_purity]}

4.5 *For Research Use Only !

{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

Change View

Size Price VIP Price

US Stock

Global Stock

In Stock
{[ item.pr_size ]} Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

  • {[ item.pr_size ]}

In Stock

- +

Please Login or Create an Account to: See VIP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

  • 1-2 Day Shipping
  • High Quality
  • Technical Support
Product Citations

Alternative Products

Product Details of [ 27277-03-8 ]

CAS No. :27277-03-8
Formula : C3H6N4O
M.W : 114.11
SMILES Code : OCC1=NNC(N)=N1
MDL No. :MFCD02933180
InChI Key :WQWSMVWRGAFPJX-UHFFFAOYSA-N
Pubchem ID :222697

Safety of [ 27277-03-8 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319-H335
Precautionary Statements:P233-P260-P261-P264-P271-P280-P302+P352-P304-P304+P340-P305+P351+P338-P312-P321-P332+P313-P337+P313-P340-P362-P403-P403+P233-P405-P501

Application In Synthesis of [ 27277-03-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 27277-03-8 ]

[ 27277-03-8 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 27277-03-8 ]
  • [ 80370-42-9 ]
  • [ 877132-28-0 ]
YieldReaction ConditionsOperation in experiment
In acetic acid; at 60℃; for 18h; 5-Amino-1H-[1,2,4]triazol-3-yl)-methanol (Bru-Magniez et al US (1995) US 5387747 A19950207) (7.9g, 41.6mmol) was mixed with <strong>[80370-42-9]2-formyl-3-oxo-propionic acid ethyl ester</strong> (Torri Sigeri et al Synthesis (1986) 5 pg 400-402), (6.0g, 41.6mmol) in acetic acid (30ml). The reaction mixture was heated to 60°C for 18hrs. After which time the mixture was cooled to room temperature and diluted with diethyl ether (200ml). Product crashes out of solution. The solids are then filtered and washed with diethyl ether (200ml), product dried in vacc oven for 5 hrs. To afford title compound as a white solid (8.0g). 1H NMR (300MHz, CDCI3): 5 1.47 (t, J=6.97, Hz, 3 H) 3.00 (bs, 1 H) 4.53 (q, J=7.16 Hz, 2 H), 5.00 (s, 2 H) 9.40 (d, J=2.07, Hz, 1 H) 9.50 (d, J=2.07, Hz, 1 H)
 

Historical Records

Technical Information

Categories

Related Functional Groups of
[ 27277-03-8 ]

Alcohols

Chemical Structure| 63870-39-3

A114776 [63870-39-3]

(3-Amino-1H-1,2,4-triazol-5-yl)methanol compound with 2-hydroxyacetic acid

Similarity: 0.88

Amines

Chemical Structure| 105445-19-0

A728744 [105445-19-0]

3-(Methoxymethyl)-1H-1,2,4-triazol-5-amine

Similarity: 0.93

Chemical Structure| 63870-39-3

A114776 [63870-39-3]

(3-Amino-1H-1,2,4-triazol-5-yl)methanol compound with 2-hydroxyacetic acid

Similarity: 0.88

Chemical Structure| 4923-01-7

A158293 [4923-01-7]

5-Methyl-4H-1,2,4-triazol-3-amine

Similarity: 0.84

Chemical Structure| 53741-81-4

A275060 [53741-81-4]

5-Methyl-1H-1,2,4-triazol-3-amine

Similarity: 0.84

Chemical Structure| 304655-78-5

A361230 [304655-78-5]

3-Amino-1H-1,2,4-triazole-5-carboxylic acid hydrate

Similarity: 0.83

Related Parent Nucleus of
[ 27277-03-8 ]

Triazoles

Chemical Structure| 105445-19-0

A728744 [105445-19-0]

3-(Methoxymethyl)-1H-1,2,4-triazol-5-amine

Similarity: 0.93

Chemical Structure| 63870-39-3

A114776 [63870-39-3]

(3-Amino-1H-1,2,4-triazol-5-yl)methanol compound with 2-hydroxyacetic acid

Similarity: 0.88

Chemical Structure| 4923-01-7

A158293 [4923-01-7]

5-Methyl-4H-1,2,4-triazol-3-amine

Similarity: 0.84

Chemical Structure| 53741-81-4

A275060 [53741-81-4]

5-Methyl-1H-1,2,4-triazol-3-amine

Similarity: 0.84

Chemical Structure| 304655-78-5

A361230 [304655-78-5]

3-Amino-1H-1,2,4-triazole-5-carboxylic acid hydrate

Similarity: 0.83