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Chemical Structure| 27171-88-6 Chemical Structure| 27171-88-6
Chemical Structure| 27171-88-6
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Product Details of [ 27171-88-6 ]

CAS No. :27171-88-6
Formula : C11H13ClN2O2
M.W : 240.69
SMILES Code : O=C(OCC)/C(Cl)=N/NC1=CC=C(C)C=C1
MDL No. :MFCD02065467

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Application In Synthesis of [ 27171-88-6 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 27171-88-6 ]

[ 27171-88-6 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 36822-11-4 ]
  • [ 27171-88-6 ]
  • ethyl 1-(4-methylphenyl)-7-phenyl-1,2,4-triazolo[4,3-a]-5(1H)-pyrimidinone-3-carboxylate [ No CAS ]
  • 2
  • [ 545445-44-1 ]
  • [ 27171-88-6 ]
  • C27H28N4O4 [ No CAS ]
YieldReaction ConditionsOperation in experiment
79.3% With triethylamine; In ethyl acetate; at 80℃;Inert atmosphere; The lg (280mg, 0. 79mmol) was dissolved in ethyl acetate (10ml), and added at room temperature [(4-methylphenyl)hydrazono]chloroacetic acid ethyl ester (246mg, 1.02mmol), triethylamine (242mg , 2. 4mmol) to give a reaction mixture, and the reaction mixture was refluxed overnight at 80 C under. Tracking progress of the reaction by TLC, the reaction was completed, slowly added dropwise 4Nu HC1 (1.6ml) at room temperature to obtain a reaction mixture, said reaction mixture at room temperature overnight. TLC withTrack progress of the reaction, the reaction was complete, was purified by column chromatography lh (295mg, yellow solid), yield: 79.3%
 

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