Home Cart Sign in  
Chemical Structure| 26933-87-9 Chemical Structure| 26933-87-9

Structure of 26933-87-9

Chemical Structure| 26933-87-9

*Storage: {[sel_prStorage]}

*Shipping: {[sel_prShipping]}

,{[proInfo.pro_purity]}

4.5 *For Research Use Only !

{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

Change View

Size Price VIP Price

US Stock

Global Stock

In Stock
{[ item.pr_size ]} Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

  • {[ item.pr_size ]}

In Stock

- +

Please Login or Create an Account to: See VIP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

  • 1-2 Day Shipping
  • High Quality
  • Technical Support
Product Citations

Product Citations

Arachchige, Kavinda M ; Vrionides, Michael A ; Wijesinghe, Kaveesha J ; Mani, Tomoyasu ; Abeywickrama, Chathura S ;

Abstract: Pyrene-based small-molecule fluorescent dyes have been widely used in biomedical imaging and sensing applications. Among them, pyrene-based π-acceptor (π-A) type probes are an important class of fluorescent dyes due to their ability to produce a large Stokes’ shift (Δλ >100 nm) by strong intramolecular charge transfer (ICT) process. In this work, a pyrene-benzothiazolium-based π-A probe (ETP-2) was synthesized in good yield to study its imaging applications while comparing with previously developed regio-isomer ETP-1. ETP-2 exhibited a large Stokes shift (Δλ ≈100-150 nm) and a bright red-emission (λem ≈610–630 nm) due to strong intramolecular charge transfer (ICT) effect. The behaviour of the two regioisomers (ETP-2 and ETP-1) were studied by different photophysical methods including optical spectroscopy, transient absorption (TA) spectroscopy, fluorescence lifetime measurements, and low-temperature fluorescence. Sub-cellular specificity of ETP-2 was studied with several fluorescent markers (mitochondria, lysosome, nucleus, endoplasmic reticulum, and Golgi) and ETP-2 exhibited an exceptional lysosome specificity in A-172 cells (Pearson’s correlation coefficient calc. ≈0.9). Fluorescence confocal microscopy imaging and fluorescence spectroscopy-based studies indicated strong evidence to support possible localization of ETP-2 into the membrane regions of the lysosomes.

Keywords: Pyrene-benzothiazolium ; Regio-effect ; Fluorescent dyes ; Fluorescence confocal microscopy imaging ; Lysosome

Purchased from AmBeed: ;

Alternative Products

Product Details of [ 26933-87-9 ]

CAS No. :26933-87-9
Formula : C17H10O
M.W : 230.26
SMILES Code : O=CC1=CC2=CC=C3C=CC=C4C=CC(C2=C34)=C1
MDL No. :MFCD00064972

Safety of [ 26933-87-9 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319-H335
Precautionary Statements:P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P362-P403+P233-P501

Application In Synthesis of [ 26933-87-9 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 26933-87-9 ]

[ 26933-87-9 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 781-17-9 ]
  • [ 26933-87-9 ]
  • 2
  • [ 26933-87-9 ]
  • [ 78364-55-3 ]
  • 6-fluoro-2-[2-((pyren-2-yl)methylene)hydrazino]benzothiazole [ No CAS ]
YieldReaction ConditionsOperation in experiment
72% With acetic acid; In ethanol; at 80℃; for 0.166667h;Microwave irradiation; General procedure: 2-(2-Arylidenehydrazino)-6-fluorobenzothiazoles 6a-r. General Procedure D. A mixture of compound 2 (0.0549 g, 0.0003 mol), the appropriate aromatic aldehyde (0.00033 mol) and glacial acetic acid (0.1 mL) in ethanol (5 mL) was heated under microwave (20 W) at 80 °C for 10 min. On cooling, the precipitated solid was collected by filtration, washed with water, dried and crystallized from the appropriate solvent to give the desired compounds 6a-r.
 

Historical Records