Home Cart Sign in  
Chemical Structure| 2687-92-5 Chemical Structure| 2687-92-5

Structure of 2687-92-5

Chemical Structure| 2687-92-5

*Storage: {[sel_prStorage]}

*Shipping: {[sel_prShipping]}

,{[proInfo.pro_purity]}

4.5 *For Research Use Only !

{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

Change View

Size Price VIP Price

US Stock

Global Stock

In Stock
{[ item.pr_size ]} Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

  • {[ item.pr_size ]}

In Stock

- +

Please Login or Create an Account to: See VIP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

  • 1-2 Day Shipping
  • High Quality
  • Technical Support
Product Citations

Alternative Products

Product Details of [ 2687-92-5 ]

CAS No. :2687-92-5
Formula : C8H15NO
M.W : 141.21
SMILES Code : O=C1N(CC(C)C)CCC1
MDL No. :MFCD00968497

Safety of [ 2687-92-5 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H227-H303-H318-H360
Precautionary Statements:P201-P202-P210-P280-P305+P351+P338+P310-P312-P370+P378-P403+P235-P405-P501

Application In Synthesis of [ 2687-92-5 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 2687-92-5 ]

[ 2687-92-5 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 2687-92-5 ]
  • [ 228251-24-9 ]
  • [ 74-88-4 ]
  • [ 741702-69-2 ]
YieldReaction ConditionsOperation in experiment
Reference Example 13 To N-isobutyl-2-pyrrolidone (1.28 g) was added an aqueous methanesulfonic acid solution (3.5 g/4.7 ml), and the mixture was refluxed at 130C for 3 days. The mixture was returned to room temperature, and sodium carbonate (1.92 g) was slowly added thereto. The resulting solution was added dropwise at 90C to a suspension of <strong>[228251-24-9]5-bromo-2-chloronicotinaldehyde</strong> (1.0 g) and sodium carbonate (1.56 g) in DMSO (13 ml), and the mixture as it is was stirred for 4 hours, followed by cooling to 0C. Water was added thereto, 6 N hydrochloric acid (5 ml) was then added, and the mixture was extracted with ethyl acetate. The organic layer was washed with water and saturated brine, and dried over magnesium sulfate. The solvent was distilled off under reduced pressure and the residue as it is was dissolved in DMF (20 ml). Potassium carbonate (1.25 g) and iodomethane (0.57 ml) were added thereto, and the mixture was stirred at room temperature under a nitrogen atmosphere for 2 hours. Water was added thereto and the mixture was extracted with ethyl acetate. The organic layer was washed with saturated brine, and dried over magnesium sulfate. The solvent was distilled off under reduced pressure and the resulting residue was purified by silica gel column chromatography (hexane: ethyl acetate = 12: 1 ? hexane: ethyl acetate = 4: 1) to give methyl 4-[(5-bromo-3-formylpyridin-2-yl)(isobutyl)amino]butanote (763 mg) as a yellow oily material. 1H-NMR (300MHz, CDCl3) delta 0.82 (6H, d, J=6.6 Hz), 1.88-2.04 (3H, m), 2.27 (2H, t, J=7.2 Hz), 3.28 (2H, d, J=7.5 Hz), 3.51 (2H, t, J=7.5 Hz), 3.64 (3H, s), 8.02 (1H, d, J=2.7 Hz), 8.32 (1H, d, J=2.7 Hz), 9.89 (1H, s).
 

Historical Records