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Chemical Structure| 26750-81-2 Chemical Structure| 26750-81-2
Chemical Structure| 26750-81-2

Alibendol

CAS No.: 26750-81-2

Alibendol is used as an antispasmodic, choleretic, and cholekinetic agent.

Synonyms: EB 1856

4.5 *For Research Use Only !

Cat. No.: A192206 Purity: 98%

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Product Details of Alibendol

CAS No. :26750-81-2
Formula : C13H17NO4
M.W : 251.28
SMILES Code : O=C(NCCO)C1=CC(CC=C)=CC(OC)=C1O
Synonyms :
EB 1856
MDL No. :MFCD00865165
InChI Key :UMJHTFHIQDEGKB-UHFFFAOYSA-N
Pubchem ID :71916

Safety of Alibendol

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of Alibendol

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 26750-81-2 ]

[ 26750-81-2 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 85614-43-3 ]
  • [ 141-43-5 ]
  • [ 26750-81-2 ]
YieldReaction ConditionsOperation in experiment
8.8 g In toluene; for 12h;Reflux; Inert atmosphere; Under a nitrogen atmosphere, 11.2 g of <strong>[85614-43-3]methyl 2-hydroxy-3-methoxy-5-allylbenzoate</strong> (5) and 80 ml of toluene were added to the reaction flask.After stirring uniformly, 12 ml of ethanolamine was added dropwise, and the mixture was heated under reflux for 12 hours.After completion of the reaction, the temperature was lowered, and the toluene phase was washed with 25 ml of 5% diluted hydrochloric acid, dried over anhydrous sodium sulfate and evaporated to dryness.The crude product was purified by recrystallization from 5 times benzene.The white powder alibendol 8.8 g was obtained in a purity of 98.6%.
 

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