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Chemical Structure| 25297-51-2 Chemical Structure| 25297-51-2

Structure of 25297-51-2

Chemical Structure| 25297-51-2

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Product Details of [ 25297-51-2 ]

CAS No. :25297-51-2
Formula : C11H7Cl2N
M.W : 224.09
SMILES Code : ClC1=CC(C2=CC=CC=C2)=CC(Cl)=N1
MDL No. :MFCD09030072
InChI Key :HLBKNKSYLIRLPK-UHFFFAOYSA-N
Pubchem ID :11322048

Safety of [ 25297-51-2 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of [ 25297-51-2 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 25297-51-2 ]

[ 25297-51-2 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 87486-37-1 ]
  • [ 536-74-3 ]
  • [ 18700-11-3 ]
  • [ 27296-22-6 ]
  • [ 25297-51-2 ]
  • [ 106719-02-2 ]
  • 2
  • [ 25297-51-2 ]
  • [ 439090-73-0 ]
  • C37H23N3O2 [ No CAS ]
YieldReaction ConditionsOperation in experiment
64.7% With potassium phosphate; palladium diacetate; In N,N-dimethyl-formamide; at 150.0℃; for 24.0h;Inert atmosphere; In a 250 mL three-necked flask, nitrogen gas was introduced, 0.01 mol of intermediate A1, 150 ml of DMF, 0.03 mol of intermediate B1, 0.0002 mol of palladium acetate were added, stirred, and then 0.02 mol of K3PO4 aqueous solution was added, heated to 150 C, refluxed for 24 hours, and sampled. Point plate, the reaction is complete. It is naturally cooled, extracted with 200 ml of dichloromethane, and the layers are separated. The extract is dried over anhydrous sodium sulfate, filtered, and the filtrate is evaporated to silicaThe HPLC purity was 99.4%, and the yield was 64.7%
 

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