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Chemical Structure| 252263-98-2 Chemical Structure| 252263-98-2

Structure of 252263-98-2

Chemical Structure| 252263-98-2

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Product Details of [ 252263-98-2 ]

CAS No. :252263-98-2
Formula : C14H18N2O3
M.W : 262.30
SMILES Code : N#CC1=CC=CC(OCCNC(OC(C)(C)C)=O)=C1
MDL No. :MFCD18070988

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Application In Synthesis of [ 252263-98-2 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 252263-98-2 ]

[ 252263-98-2 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 252263-98-2 ]
  • [ 120351-94-2 ]
YieldReaction ConditionsOperation in experiment
With hydrogenchloride; In 1,4-dioxane; sodium hydroxide; dichloromethane; ethyl acetate; Step 3 Synthesis of 3-(2-aminoethoxy)benzonitrile: 1.41 g of 3-[2-(t-butoxycarbonylamino)ethoxy]benzonitrile was dissolved in 20 ml of 4 N solution of hydrogen chloride in dioxane, and the solution was stirred at room temperature for 2 hours. The solvent was evaporated. The residue was suspended in dichloromethane, and the obtained suspension was filtered to obtain hydrochloride of the title compound. Yield: 0.89 g (4.48 mmol) (83 %). The hydrochloride was dissolved in 1 N aqueous sodium hydroxide solution. After the treatment with ethyl acetate as the extractant in an ordinary manner, the title compound was obtained. H-NMR (CDCl3) delta 3.10 (2H,t), 4.00 (2H, t), 7.15 (1H, d), 7.17 (1H, s), 7.25 (1H, d), 7.37 (1H, t).
  • 2
  • [ 873-62-1 ]
  • [ 158690-56-3 ]
  • [ 252263-98-2 ]
 

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