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Chemical Structure| 248590-47-8 Chemical Structure| 248590-47-8

Structure of 248590-47-8

Chemical Structure| 248590-47-8

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Product Details of [ 248590-47-8 ]

CAS No. :248590-47-8
Formula : C28H24O4
M.W : 424.49
SMILES Code : OC=1C2=CC=CC1CC3=CC=CC(=C3O)CC=4C=CC=C(C4O)CC=5C=CC=C(C5O)C2

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Application In Synthesis of [ 248590-47-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 248590-47-8 ]

[ 248590-47-8 ] Synthesis Path-Downstream   1~4

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  • [ 248590-47-8 ]
  • [ 118591-58-5 ]
  • [ 537041-50-2 ]
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  • [ 13920-91-7 ]
  • [ 248590-47-8 ]
  • [ 1394800-17-9 ]
  • 4
  • [ 40299-87-4 ]
  • [ 248590-47-8 ]
  • [ 1558817-92-7 ]
YieldReaction ConditionsOperation in experiment
66% With potassium carbonate; In acetonitrile;Reflux; To a suspension of calix[4]arene (2) (1.0 g, 2.36 mmol) in acetonitrile (50 mL) was added K2CO3 (1.95 g, 14 mmol) and 2-bromo-1-morpholinoethanone (2.94 g, 14.1 mmol). The suspension was stirred at reflux overnight, resulting in a brown suspension. Solvents were removed, and the residue was partitioned between water (100 mL) and CH2Cl2 (100 mL). The organic layer was removed and the water layer was extracted again with CH2Cl2 (50 mL). The combined organic layers were then further washed with water (100 mL) and dried (Na2SO4), and the solvent was removed under reduced pressure. The resulting solid was recrystallised from ethanol to give the title compound (1.44 g, 66%) (m.p.: 218 C). 1H NMR (400 MHz, CDCl3, deltaH): 6.60-6.67 (m, 12H, Ar-H), 4.98 (d, J = 14 Hz, 4H, Ar-CH2-Ar), 4.91 (s, 4H, ArO-CH2-C(O)), 3.49-3.69 (m, 32H, N(CH2CH2)2O), 3.26 (d, J = 14 Hz, Ar-CH2-Ar). 13C NMR (100 MHz, CDCl3, deltaC): 167.6, 155.4,134.1, 128.1, 122.2, 70.8, 66.4, 66.2, 44.4, 41.2, 31.1. IR (nu, cm-1): 3445, 2967, 2912, 2863, 1676, 1658, 1466, 1448, 1466, 1358, 1299, 1274, 1213, 1236, 1196, 1112,1095, 1068, 1026, 998, 911, 852, 778, 754. ES-MS (m/z): 955.38 (M + Na). Required for C52H60N4O12·H2O: C, 65.67; H, 6.57; N, 5.89. Found: C, 65.88; H, 6.49; N, 5.65.
 

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