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Chemical Structure| 2315-36-8 Chemical Structure| 2315-36-8

Structure of 2315-36-8

Chemical Structure| 2315-36-8

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Product Details of [ 2315-36-8 ]

CAS No. :2315-36-8
Formula : C6H12ClNO
M.W : 149.62
SMILES Code : O=C(N(CC)CC)CCl
MDL No. :MFCD00000928
InChI Key :CQQUWTMMFMJEFE-UHFFFAOYSA-N
Pubchem ID :16844

Safety of [ 2315-36-8 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H315-H319-H330-H335-H302+H312
Precautionary Statements:P264-P270-P271-P280-P284-P302+P352-P304+P340-P305+P351+P338-P310-P330-P361+P364-P403+P233-P405-P501
Class:6.1
UN#:2810
Packing Group:

Application In Synthesis of [ 2315-36-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 2315-36-8 ]

[ 2315-36-8 ] Synthesis Path-Downstream   1~5

  • 1
  • [ 4877-80-9 ]
  • [ 2315-36-8 ]
  • N,N-Diethyl-2-(3,6,7,10,11-pentakis-diethylcarbamoylmethoxy-triphenylen-2-yloxy)-acetamide [ No CAS ]
  • 2
  • [ 22876-16-0 ]
  • [ 2315-36-8 ]
  • <i>N</i>,<i>N</i>-diethyl-2-(6-methyl-2-oxo-benzooxazol-3-yl)-acetamide [ No CAS ]
  • 3
  • [ 24985-85-1 ]
  • [ 2315-36-8 ]
  • [ 380240-99-3 ]
  • 5-diethylcarbamoylmethoxy-1H-indole-2-carboxylic acid ethyl ester [ No CAS ]
YieldReaction ConditionsOperation in experiment
With caesium carbonate; In N-methyl-acetamide; Example 4 Preparation of 5-(2-diethylamino-ethoxy)-1H-indole-2-carbaldehyde A mixture of <strong>[24985-85-1]5-hydroxy-1H-indole-2-carboxylic acid ethyl ester</strong> (1 g, 5 mmol), 2-chloro-N,N-diethylacetamide (1 mL, 7.5 mmol) and cesium carbonate (5 g, 15 mmol) in dimethylformamide (10 mL) was stirred at room temperature for 6 hours. The reaction was diluted with ethyl acetate (160 mL), washed with water (5*50 mL) and brine, dried and concentrated. The residue was recrystallized from ethyl acetate and hexane to give 0.52 g of 5-diethylcarbamoylmethoxy-1H-indole-2-carboxylic acid ethyl ester as an off-white solid. 1H-NMR (360 MHz, DMSO-d6) delta 11.70 (s, br, 1H, NH), 7.34 (d, J=9.0 Hz, 1H, H-7), 7.08 (d, J=2.3 Hz, 1H, H-4), 7.02 (s, 1H, H-3), 6.94 (dd, J=2.3 & 9.0 Hz, 1H, H-6), 4.71 (s, 2H, OC2CON(CH2CH3)2, 4.31 (q, J=7.2 Hz, 2H, OC2CH3), 3.25-3.38 (m, 4H, N(C2CH3)2, 1.32 (t, J=7.2 Hz, 3H, OCH2C3) 1.15 (t,J=7.0 Hz,3H, NCH2C3), 1.03 (t,J=7.0 Hz, 3H, NCH2CH3). MS-EI m/z 318 [M+].
  • 4
  • [ 52764-11-1 ]
  • [ 2315-36-8 ]
  • [ 62843-76-9 ]
YieldReaction ConditionsOperation in experiment
With sodium methylate; In methanol; dimethyl sulfoxide; EXAMPLE 1 N,N-diethyl-(2,6-dichloro-3-pyridyl)-oxy-acetic acid amide A solution of 4.6 g of sodium methylate (0.2 mole) in 50 ml of absolute methanol is slowly added at room temperature to 33.4 g (0.2 mole) of <strong>[52764-11-1]2,6-dichloropyridin-3-ol</strong>. There is then added, with gentle heating, 100 to 150 ml of dimethylsulphoxide until the cloudy solution becomes clear. The solution is then heated to 80-90 and methanol is distilled off. The reaction solution is cooled and an addition is slowly made dropwise at 0-10 C of a solution of 60 g (0.2 mole) of chloroacetic acid diethylamide (dissolved in 300 ml of dimethylsulphoxide). After the dropwise addition is completed, the reaction mixture is stirred at room temperature for a further hour. The solvent is distilled off under reduced pressure; the oil remaining is taken up in ether, washed with water, dried and freed from solvent to leave N,N-diethyl-(2,6-dichloro-3-pyridyl)-oxy-acetic acid amide, which boils at 137/0.4 torr; yield: 35 g (62% of theory).
  • 5
  • [ 114046-25-2 ]
  • [ 2315-36-8 ]
  • 3-(4-cyanophenyl)-N,N-diethyl-1-(4-methoxyphenyl)aziridine-2-carboxamide [ No CAS ]
 

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